DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5390 and Tmprss9

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_006513905.2	Gene:	Tmprss9 / 432478	MGIID:	3612246	Length:	1342	Species:	Mus musculus

Alignment Length:	299	Identity:	92/299 - (30%)
Similarity:	137/299 - (45%)	Gaps:	45/299 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 PNKRKDPIFEFKPDH------PEGCGYQNPNGVGFKITGAVNQEAEFGEFPWMLAILREEGNLNL 175
            |.....|:    |.|      |:.||.:.......:|.|.::  |..||.||..::  :||..:.
Mouse   725 PTAAPSPV----PLHPSTTAKPQECGARPAMDKPTRIVGGIS--AVSGEVPWQASL--KEGPRHF 781

  Fly   176 YECGGALIAPNVVLTAAHCVHNKQPSSI------VVRAGEWDTQTQTEIRRHEDRYVKEIIYHEQ 234
              ||..::....:|:||||.::.:...:      |...|...:..:..:||        :..|.:
Mouse   782 --CGATVVGDRWLLSAAHCFNHTKVEQVQAHLGTVSLLGVGGSPVKLGLRR--------VALHPR 836

  Fly   235 FNKGSLYNDVAVMLLESPFTLQENIQTVCLPNVGDKFDFDR-CYATGWGKNKFGKDGEYQVILKK 298
            :|.|.|..|||::.|..|....:.||.||||....||...| |..:|||..:.| :.....||:|
Mouse   837 YNPGILDFDVALLELAQPLVFNKYIQPVCLPLAIHKFPVGRKCMISGWGNMQEG-NATKPDILQK 900

  Fly   299 VDMPVVPEQQCETNLRETRLGRHFILHDSFICAGG-EKDKDTCKGDGGSPLVCPIAGQKNRFKSA 362
            ..:.::.::.|....       :|.|.|..:|||. |...|:|:||.|.||.|  ......|..|
Mouse   901 ASVGIIEQKMCGALY-------NFSLTDRMLCAGFLEGRVDSCQGDSGGPLAC--EETPGVFYLA 956

  Fly   363 GIVAWGIGCGEVNIPGVYASVAKLRPWIDAKLKIWSIDP 401
            |||:|||||.:...|||||.:.:|:.||   ||..|.||
Mouse   957 GIVSWGIGCAQAKKPGVYARITRLKDWI---LKAMSSDP 992

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	77/245 (31%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	76/244 (31%)
Tmprss9	XP_006513905.2	SEA	285..365	CDD:366610
		LDLa	407..442	CDD:238060
		Tryp_SPc	455..684	CDD:214473
		Tryp_SPc	756..984	CDD:214473	78/251 (31%)
		Tryp_SPc	1085..1336	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910