DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and proca

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_956650.1	Gene:	proca / 393327	ZFINID:	ZDB-GENE-060824-5	Length:	434	Species:	Danio rerio

Alignment Length:	359	Identity:	106/359 - (29%)
Similarity:	155/359 - (43%)	Gaps:	80/359 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 KECVPRWLCANDTINTSGDGIIDIRLGTDAEC---KNYLDLCCDL-------PNKRKDPIFEFKP 129
            |.|..|....|.::| :||        .|.:|   |:.|...|..       .|.||     ..|
Zfish   117 KHCDLRRTATNCSLN-NGD--------CDHDCHESKDGLARTCSCIKGYQLQDNSRK-----CTP 167

  Fly   130 DHPEGCG--------YQN-PNGV--GFKITGAVNQEAEFGEFPWMLAILREEGNLNLYECGGALI 183
            .:...||        |.| |..|  .:.:.|.|.:.   ||.||...||   .:|..:.|||.||
Zfish   168 KNDASCGQIRIPKSAYANKPKPVLQPWVMGGNVGKR---GESPWQALIL---NHLGRFHCGGVLI 226

  Fly   184 APNVVLTAAHCVHNKQPSSIVVRAGEWD------TQTQTEIRRHEDRYVKEIIYHEQFNKGSLYN 242
            ..|.|||||||:...  |...||.|::.      ::....:::|        |.|.|:|..::.|
Zfish   227 DENWVLTAAHCLETS--SKFSVRLGDYQRFKFEGSEVTLPVKQH--------ISHPQYNPITVDN 281

  Fly   243 DVAVMLLESPFTLQENIQTVCLPNVG-DKFDFDR----CYATGWGKNKFGKDGEYQVILKKVDMP 302
            |:|::.|:.|......|...|||::. .|....|    ...||||||..... .|...|..|::|
Zfish   282 DIALLRLDGPVKFSTYILPACLPSLELAKRMLHRNGTVTIITGWGKNNQSAT-SYNSTLHYVELP 345

  Fly   303 VVPEQQCETNLRETRLGRHFI--LHDSFICAG--GEKDKDTCKGDGGSPLVCPIAGQKNRFKSAG 363
            :|..::|         .||.:  |.|:.:|||  |:. ||.|:||.|.|::...   .:.:...|
Zfish   346 IVDNKEC---------SRHMMNNLSDNMLCAGVLGQV-KDACEGDSGGPMMTLF---HDTWFLVG 397

  Fly   364 IVAWGIGCGEVNIPGVYASVAKLRPWIDAKLKIW 397
            :|:||.|||:.:..|:|..||....|||:..:.|
Zfish   398 LVSWGEGCGQRDKLGIYTKVASYLDWIDSVRQGW 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	79/252 (31%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	78/251 (31%)
proca	NP_956650.1	GLA	23..84	CDD:214503
		EGF_CA	85..119	CDD:238011	1/1 (100%)
		FXa_inhibition	128..165	CDD:291342	11/50 (22%)
		Tryp_SPc	195..427	CDD:238113	83/261 (32%)
		Tryp_SPc	197..424	CDD:214473	80/256 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910