DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and flz

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster

Alignment Length:	376	Identity:	111/376 - (29%)
Similarity:	169/376 - (44%)	Gaps:	78/376 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 DKLISDIFKTDETPKPSSPPPPVVNPKDSSGSTGSENGGSSSTQYQSCGDQKECVPRWLCANDTI 88
            |:::.:..:.|..|.||.      |..| .|:|.|..||::..:..|                |.
  Fly  1380 DEIVDEEDEEDVNPNPSD------NEID-QGATLSSYGGANGRKIHS----------------TS 1421

  Fly    89 NTSGDGIIDIRLGTDAECKNYLDLCCDLPNKRKDPIFEFKPDHPEGCGYQNPNGVGFKITGAVNQ 153
            .|                         ||.    |...|.....| ||.: |:....:|.|  .:
  Fly  1422 RT-------------------------LPT----PNLAFHSPSTE-CGVR-PHVKSGRIVG--GK 1453

  Fly   154 EAEFGEFPWMLAILREEGNLNLY---ECGGALIAPNVVLTAAHCVHNKQP---SSIVVRAGEWDT 212
            .:.||.:||.: ::||...|.|:   :|||.||....|:|||||    ||   :|:|...||:|.
  Fly  1454 GSTFGAYPWQV-LVRESTWLGLFTKNKCGGVLITSRYVITAAHC----QPGFLASLVAVMGEFDI 1513

  Fly   213 QTQTEIRRHEDRYVKEIIYHEQFNKGSLYNDVAVMLLESPFTLQENIQTVCLPNVGDKFDFDRCY 277
            ....|.:|...:.||.:|.|.|::..:..||:|::.|:||.....:|..:|:||  |..||....
  Fly  1514 SGDLESKRSVTKNVKRVIVHRQYDPATFENDLALLELDSPVQFDTHIVPICMPN--DVADFTGRM 1576

  Fly   278 A--TGWGKNKFGKDGEYQVILKKVDMPVVPEQQCETNLRETRLGRHFILHDSFICAG-GEKDKDT 339
            |  ||||:.|:|  |....:|::|.:|::....|:......  |.:..:..||:||| ....||:
  Fly  1577 ATVTGWGRLKYG--GGVPSVLQEVQVPIIENSVCQEMFHTA--GHNKKILTSFLCAGYANGQKDS 1637

  Fly   340 CKGDGGSPLVCPIAGQKNRFKSAGIVAWGIGCGEVNIPGVYASVAKLRPWI 390
            |:||.|.|||  :.....|::.||.|:.||.|....:||||......:||:
  Fly  1638 CEGDSGGPLV--LQRPDGRYELAGTVSHGIKCAAPYLPGVYMRTTFYKPWL 1686

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	86/247 (35%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	85/245 (35%)
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	88/253 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457476
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840