DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5390 and PRSS53

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_011544118.1	Gene:	PRSS53 / 339105	HGNCID:	34407	Length:	623	Species:	Homo sapiens

Alignment Length:	292	Identity:	66/292 - (22%)
Similarity:	111/292 - (38%)	Gaps:	71/292 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 GEFPWMLAILREEGNLNLYECGGALIAPNVVLTAAHCVHNKQPSSIVVRAGEWDTQTQTEIRRH- 221
            ||:||..::.|:..::    |.|:|:|...|||||||......:.:    ..|.. ....::|.
Human    46 GEWPWQASVRRQGAHI----CSGSLVADTWVLTAAHCFEKAAATEL----NSWSV-VLGSLQREG 101

  Fly   222 -----EDRYVKEIIYHEQFNKGSLYNDVAVMLLESPFTLQENIQTVCLPNVGDKFDFD-RCYATG 280
                 |:..|..:.....:|..|..:|:|::.|..|.|    ...:|||....:|.|. .|:|||
Human   102 LSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTT----HTPLCLPQPAHRFPFGASCWATG 162

  Fly   281 WGKNKFGKDGEYQVILK------------------KVDMPVVPEQQ----------CETNLRETR 317
            |.::.  .||:....||                  ....|::|..|          ....||..|
Human   163 WDQDT--SDGKCWPRLKLGEALCLPSVTVSAPNCPGFQSPLLPRSQTLAPAPSLSPAPGTLRNLR 225

  Fly   318 L----------------GRHFI--LHDSFICAGGEKD-KDTCKGDGGSPLVCPIAGQKNRFKSAG 363
            |                .||..  .....:|.|.:.. :..|:||.|.|::|  ......:..||
Human   226 LRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLC--LEPDGHWVQAG 288

  Fly   364 IVAWGIGCGEVNIPGVYASVAKLRPWIDAKLK 395
            |:::...|.:.:.|.:..:.|....|:.|:::
Human   289 IISFASSCAQEDAPVLLTNTAAHSSWLQARVQ 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	65/286 (23%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	64/285 (22%)
PRSS53	XP_011544118.1	Tryp_SPc	42..316	CDD:238113	65/286 (23%)
		Tryp_SPc	43..314	CDD:214473	64/284 (23%)
		Tryp_SPc	359..>512	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910