DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and tmprss4b

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_001119849.1	Gene:	tmprss4b / 327651	ZFINID:	ZDB-GENE-030131-5862	Length:	432	Species:	Danio rerio

Alignment Length:	254	Identity:	77/254 - (30%)
Similarity:	121/254 - (47%)	Gaps:	39/254 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 KITGAVNQEAEFGEFPWMLAILREEGNLNLYECGGALIAPNVVLTAAHCV--HNKQPSSIVVRAG 208
            :|.|.|  |.....:||.:::.....::    |||:|::.:.:::||||.  ..::.|...|..|
Zfish   201 RIVGGV--ETSIEHWPWQVSLQFNHRHM----CGGSLLSTSWIISAAHCFTGRTQELSRWTVVLG 259

  Fly   209 EWDTQTQTEIRRHEDRYVKEIIYHEQFNKGSLYNDVAVMLLESPFTLQENIQTVCLP--NVGDKF 271
                  ||::.......|..|:.|:.:|:.:...|:|::.|..|....|:|..||||  .:..|
Zfish   260 ------QTKVMDVVGVSVDMIVIHKDYNRLTNDFDIAMLKLTWPVKTGESILPVCLPPHQLAIK- 317

  Fly   272 DFDRCYATGWGKNKFGKDGEYQVILKKVDMPVVPEQQCETNLRETRLGRHFILHDS----FICAG 332
              |....||||..|.|  |....:|:|..:|:|...:|         .:..|...|    .:|||
Zfish   318 --DMLVVTGWGLLKEG--GALPTVLQKASVPLVNRSEC---------SKPTIYSSSITPRMLCAG 369

  Fly   333 G-EKDKDTCKGDGGSPLVCPIAGQKNRFKSAGIVAWGIGCGEVNIPGVYASVAKLRPWI 390
            . :.:.|.|:||.|.|||.    ..:|::..|||:||:||.....|||||.|.:|..||
Zfish   370 FLQGNVDACQGDSGGPLVY----LSSRWQLIGIVSWGVGCAREGKPGVYADVTQLLDWI 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	74/247 (30%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	72/245 (29%)
tmprss4b	NP_001119849.1	SRCR_2	100..179	CDD:292133
		SRCR	105..>175	CDD:278931
		Tryp_SPc	201..424	CDD:214473	75/252 (30%)
		Tryp_SPc	202..427	CDD:238113	77/253 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000