DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and F11

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_006253206.1	Gene:	F11 / 290757	RGDID:	1309364	Length:	622	Species:	Rattus norvegicus

Alignment Length:	239	Identity:	87/239 - (36%)
Similarity:	128/239 - (53%)	Gaps:	26/239 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 GEFPWMLAILREEGNLNLYECGGALIAPNVVLTAAHCVHNKQ-PSSIVVRAGEWDTQTQTEIRRH 221
            ||:||.:.:...:|:|    |||::|....:||||||....: |.::.|..|   ...|:||  :
  Rat   397 GEWPWQVTLHTTQGHL----CGGSIIGNRWILTAAHCFSGTETPKTLRVYGG---IVNQSEI--N 452

  Fly   222 EDR---YVKEIIYHEQFNKGSLYNDVAVMLLESPFTLQENIQTVCLPNVGDK-FDFDRCYATGWG 282
            ||.   .|:|:|.|:|:.......|:|::.||......:..:.:|||:.||: .....|:.||||
  Rat   453 EDTTFFRVQEMIIHDQYTSAESGFDIALLKLEPAMNYTDFQRPICLPSKGDRNVVHTECWVTGWG 517

  Fly   283 KNKFGKDGEYQVILKKVDMPVVPEQQCETNLRETRLGRHFILHDSFICAG-GEKDKDTCKGDGGS 346
            ..| .:| |.|..|:|..:|:|..::|:|..|:.:      :.:..|||| .|..|||||||.|.
  Rat   518 YTK-SRD-EVQSTLQKAKVPLVSNEECQTRYRKHK------ITNKVICAGYKEGGKDTCKGDSGG 574

  Fly   347 PLVCPIAGQKNRFKSAGIVAWGIGCGEVNIPGVYASVAKLRPWI 390
            ||.|...|.   :...||.:||.|||:...||||.:|||...||
  Rat   575 PLSCKHNGV---WHLVGITSWGEGCGQKERPGVYTNVAKYVDWI 615

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	87/239 (36%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	85/237 (36%)
F11	XP_006253206.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..374	CDD:128519
		Tryp_SPc	387..615	CDD:214473	85/237 (36%)
		Tryp_SPc	388..615	CDD:238113	85/237 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910