DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and f7i

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_775335.1	Gene:	f7i / 282671	ZFINID:	ZDB-GENE-021206-10	Length:	443	Species:	Danio rerio

Alignment Length:	429	Identity:	101/429 - (23%)
Similarity:	158/429 - (36%)	Gaps:	131/429 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 DIFKTDETPKP-----SSPPPPVVNPKDSSG-------------STGSE---------------- 59
            ::|:.|:..|.     |:..|.:.||..::|             |.|.|
Zfish    67 EVFEDDDRTKQFWLSYSNKEPCLTNPCRNNGTCVYLADSYYCLCSEGYEGKYCEKGLEETLKCQY 131

  Fly    60 -NGG-----SSSTQYQSCGDQKECVPRWLCANDTINTSGDGIIDIRLGTDAECKNYLDLCCDLPN 118
             |||     ..|...:||    .|...:..|:|              ||  .|.:.:|..|.
Zfish   132 VNGGCEQFCDGSGARRSC----SCAEGYALADD--------------GT--SCVSQVDYPCG--- 173

  Fly   119 KRKDPIFEFKPDHPEGCGYQNPNGVGFKITGAVNQEAEFGEFPWMLAILREEGNLNLYECGGALI 183
              |.|:              ..|....:..|.::  ...|..||.:.|.....::    |||||:
Zfish   174 --KIPV--------------QKNTSQNQFLGGIH--CPRGHCPWQVLIDYNGESV----CGGALL 216

  Fly   184 APNVVLTAAHCVHNKQPSSIVVRAGEWDTQTQTEIRRHEDRY-VKEIIYHEQFNKGSLYNDVAVM 247
            ....::|||||||.|....:....||.|...   :...|:.| |..:..|..::..:|.:|:|::
Zfish   217 EGPWLITAAHCVHQKDTRFLKAVTGEHDLDV---LDGSEEPYEVSAVFIHPNYDPETLDSDLALL 278

  Fly   248 LLESPFTLQENIQTV--CLPNVGDKFDFDRCYA------TGWG--------KNKFGKDGEYQVIL 296
            .|..|  :|.::..|  |||.  .:......:|      :|||        :.:.|..|.....|
Zfish   279 RLRVP--VQRSLYAVPICLPT--PQLARSELWAARFHTLSGWGTRTAGHNLRREKGLKGPASGTL 339

  Fly   297 KKVDMPVVPEQQCETNLRETRLGRHFILHDSFICAG-GEKDKDTCKGDGGSPLVCPIAGQKNRFK 360
            :::.:|::|..|| .|...|.         :..||| .|.|..:|:|..|||||       .|:.
Zfish   340 QRLAVPLLPAAQC-GNANTTA---------NMFCAGYTEGDHASCRGHDGSPLV-------TRYG 387

  Fly   361 S----AGIVAWGIGCGEVNIPGVYASVAKLRPWIDAKLK 395
            .    .|:|:||.|||......:|..|.....|:|..:|
Zfish   388 ETSFLTGVVSWGRGCGPPGYYWIYTKVENFLIWMDTVMK 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	70/259 (27%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	69/258 (27%)
f7i	NP_775335.1	GLA	20..82	CDD:214503	3/14 (21%)
		EGF_CA	<91..120	CDD:238011	6/28 (21%)
		FXa_inhibition	129..164	CDD:291342	11/54 (20%)
		Tryp_SPc	188..420	CDD:214473	70/261 (27%)
		Tryp_SPc	188..420	CDD:238113	70/261 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910