DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and Plau

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_037217.3	Gene:	Plau / 25619	RGDID:	3343	Length:	432	Species:	Rattus norvegicus

Alignment Length:	436	Identity:	115/436 - (26%)
Similarity:	178/436 - (40%)	Gaps:	97/436 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 SCGAQDSSL---DKLISDIFKTDETPKPSSPPPPVVNPKDSSGSTGSENGGSSSTQYQSCGDQKE 76
            :||.|:..:   .|..|.|.:.....|.......:...|......|....|.::|..:.    :.
  Rat    30 NCGCQNGGVCVSYKYFSSIRRCSCPKKFKGEHCEIDTSKTCYHGNGQSYRGKANTDTKG----RP 90

  Fly    77 CVPRW---LCANDTINTSGDGIIDIRLGTDAECKN-----------------YLDLC----CDLP 117
            |: .|   .....|.|......:.:.||....|:|                 ::..|    |.|.
  Rat    91 CL-AWNSPAVLQQTYNAHRSDALSLGLGKHNYCRNPDNQRRPWCYVQIGLKQFVQECMVQDCSLS 154

  Fly   118 NKRKDPIFEFKPDHPEG--CGYQ--NPNGVGFKITGAVNQEAEFGEF------PWMLAIL--REE 170
            .|....:.:      :|  ||.:  .|.   |||.|        |||      ||..||.  .:.
  Rat   155 KKPSSTVDQ------QGFQCGQKALRPR---FKIVG--------GEFTVVENQPWFAAIYLKNKG 202

  Fly   171 GNLNLYECGGALIAPNVVLTAAHC-VHNKQPSSIVVRAGEWDTQTQTEIRRHEDRY-VKEIIYHE 233
            |:...::|||:||:|..|.:|.|| |:..:....||..|:   ..:......|.:: |:::|.||
  Rat   203 GSPPSFKCGGSLISPCWVASATHCFVNQPKKEEYVVYLGQ---SKRNSYNPGEMKFEVEQLILHE 264

  Fly   234 QFNKGSL--YNDVAVMLLES-------PFTLQENIQTVCL-PNVGD-KFDFDRCYATGWGKNKFG 287
            .|:..:|  :||:|::.:.:       |   ...|||:|| |..|| .|..| |..||:|:.. .
  Rat   265 DFSDETLAFHNDIALLKIRTSTGQCAQP---SRTIQTICLPPRFGDAPFGSD-CEITGFGQES-A 324

  Fly   288 KDGEYQVILKKVDMPVVPEQQCETNLRETRLGRHFI---LHDSFICAGGEKDK-DTCKGDGGSPL 348
            .|..|...||...:.::..:||:.        .|:.   ::...:||...:.| |:|.||.|.||
  Rat   325 TDYFYPKDLKMSVVKIISHEQCKQ--------PHYYGSEINYKMLCAADPEWKTDSCSGDSGGPL 381

  Fly   349 VCPIAGQKNRFKSAGIVAWGIGCGEVNIPGVYASVAKLRPWIDAKL 394
            :|.|.|   |...:|||:||.||.|.|.||||..|:....||.:.:
  Rat   382 ICNIDG---RPTLSGIVSWGSGCAEKNKPGVYTRVSYFLNWIQSHI 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	83/262 (32%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	82/261 (31%)
Plau	NP_037217.3	Binds urokinase plasminogen activator surface receptor	34..57		4/22 (18%)
		KR	67..152	CDD:238056	13/89 (15%)
		Connecting peptide	152..178		6/34 (18%)
		Tryp_SPc	178..420	CDD:214473	85/268 (32%)
		Tryp_SPc	179..423	CDD:238113	86/270 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910