DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and Mst1

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_038936729.1	Gene:	Mst1 / 24566	RGDID:	3114	Length:	747	Species:	Rattus norvegicus

Alignment Length:	392	Identity:	83/392 - (21%)
Similarity:	135/392 - (34%)	Gaps:	92/392 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 VNPKDSSGSTGSENGGSSS-----TQYQSCGDQKECVPRW---------LCANDTINTSGDGIID 97
            |.|:.....:|.:..||.|     .|.|....:....|::         |.||...|..||....
  Rat   405 VVPEGCYHGSGEQYRGSVSKTRKGVQCQHWSSETPHKPQFTPTSAPHAGLEANFCRNPDGDSHGP 469

  Fly    98 IRLGTDAECKNYLDLCC------DLPNKRKDPIFEFKPDHPEGCGYQNPNGVGFKITGAVNQEAE 156
            .....|.|  ...|.|.      |.|....||..:.:   .|.||.:.......::.|     ..
  Rat   470 WCYTLDPE--TLFDYCALKRCDDDQPPSILDPPVQVQ---FEKCGKRVDQSNRLRVVG-----GH 524

  Fly   157 FGEFPWMLAILREEGNLNLYECGGALIAPNVVLTAAHCV------------------HNKQPSSI 203
            .|..||.:::...:|.   :.|||:|:....||||..|:                  .|.||
  Rat   525 PGNSPWTVSLRNRQGQ---HFCGGSLVKEQWVLTARQCIWSCHDPLTGYEVWLGTINQNPQP--- 583

  Fly   204 VVRAGEWDTQTQTEIRRHEDRYVKEIIYHEQFNKGSLYNDVAVMLLESPFTLQENIQTVCLPNVG 268
                ||.:.|..:        ..|.:.       |...:.:.::.||.|..|..::..:|||  .
  Rat   584 ----GEANLQRVS--------VAKTVC-------GPAGSQLVLLKLERPVILNHHVARICLP--P 627

  Fly   269 DKF---DFDRCYATGWGKNKFGKDGEYQVILKKVDMPVVPEQQCETNLRETRLGRHFILHDSFIC 330
            :::   ....|...|||::|...:   ..:|....|.|:..|:|....|..       :.:|.||
  Rat   628 EQYVVPPGTNCEIAGWGESKGTSN---STVLHVAKMKVISSQECNVKYRRR-------VQESEIC 682

  Fly   331 AGG-EKDKDTCKGDGGSPLVCPIAGQKNRFKSAGIVAWGIGCGEVNIPGVYASVAKLRPWIDAKL 394
            ..| ......|:||.|.||.|   ...:.:...|::.....|.....|.::..|:....||:..:
  Rat   683 TEGLLAPTGACEGDYGGPLAC---YTHDCWVLQGLIIPNRVCARPRWPAIFTRVSVFVDWINKVV 744

  Fly   395 KI 396
            ::
  Rat   745 QL 746

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	55/259 (21%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	54/258 (21%)
Mst1	XP_038936729.1	PAN_1	32..111	CDD:394981
		KR	116..196	CDD:214527
		KR	199..276	CDD:214527
		KR	321..403	CDD:214527
		KR	408..490	CDD:214527	17/83 (20%)
		Tryp_SPc	520..743	CDD:238113	57/267 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910