DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5390 and Prss40

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_033382.2	Gene:	Prss40 / 21756	MGIID:	1270857	Length:	365	Species:	Mus musculus

Alignment Length:	285	Identity:	83/285 - (29%)
Similarity:	119/285 - (41%)	Gaps:	61/285 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 EGCGYQNPNGVGFKITGAVNQEAEFGEFPWMLAILREEGNLNLYE---CGGALIAPNVVLTAAHC 194
            |.||.....|   ||.|.....||  .:||       :.:|.||.   ||..||..|.||:||||
Mouse    58 EVCGKTKFQG---KIYGGQIAGAE--RWPW-------QASLRLYGRHICGAVLIDKNWVLSAAHC 110

  Fly   195 VHNKQ-PSSIVVRAGEWDTQTQTEIRRHEDRYVKEIIYHEQFNK----GSLYNDVAVMLLESPFT 254
            ....| ||...|..|..|..:.|...|  ...|:::|.|:.:|:    ||   |:.::.|.|...
Mouse   111 FQRSQEPSDYHVMLGYTDLNSPTRYSR--TMSVQKVIVHKDYNRFHTQGS---DIVLLQLRSSVE 170

  Fly   255 LQENIQTVCLPNVGDKFDFDR-CYATGWG----------KNKFGKDGEYQVILKKVDM------P 302
            ...:|...|:|....|...:: |:|:|||          .|:.   .|.::|:...|.      |
Mouse   171 YSSHILPACVPEENIKIPKEKACWASGWGYLREDVRIPLPNEL---YEAELIIMSNDQCKGFFPP 232

  Fly   303 VVPEQQCETNLRETRLGRHFILHDSFICAGG-EKDKDTCKGDGGSPLVCPIAGQKNRFKSAGIVA 366
            .||..           ||.:.::|..:||.. :..|..|.||.|.||||.:.|.   :...|:.:
Mouse   233 PVPGS-----------GRSYYIYDDMVCAADYDMSKSICAGDSGGPLVCLLEGS---WYVVGLTS 283

  Fly   367 WGIGCGE-VNIPGVYASVAKLRPWI 390
            |...|.| :..|.|:|.|:....||
Mouse   284 WSSTCEEPIVSPSVFARVSYFDKWI 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	76/265 (29%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	74/263 (28%)
Prss40	NP_033382.2	Tryp_SPc	68..308	CDD:214473	77/270 (29%)
		Tryp_SPc	69..311	CDD:238113	78/271 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	312..343
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910