DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and Proc

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_006525784.1	Gene:	Proc / 19123	MGIID:	97771	Length:	484	Species:	Mus musculus

Alignment Length:	357	Identity:	104/357 - (29%)
Similarity:	155/357 - (43%)	Gaps:	81/357 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 NGGSSSTQY---QSCGDQKECVPRWLCANDTINTSGDGIIDIRLGTDAECKNYLDLCCD-----L 116
            |||  ...|   :|.|.:..|.|.:..|:|.:                .||:.::..|.     :
Mouse   167 NGG--CLHYCLEESNGRRCACAPGYELADDHM----------------RCKSTVNFPCGKLGRWI 213

  Fly   117 PNKRK------DPIFEFKPDHPEGCGYQNPNGVGFKITGAVNQEAEFGEFPWMLAILREEGNLNL 175
            ..|||      |...|.:||         |..|...:|       :.|:.||...:|..:..|
Mouse   214 EKKRKILKRDTDLEDELEPD---------PRIVNGTLT-------KQGDSPWQAILLDSKKKL-- 260

  Fly   176 YECGGALIAPNVVLTAAHCVHNKQPSSIVVRAGEWDTQTQTEIRRHE----DRYVKEIIYHEQFN 236
             .|||.||..:.||||||||...:  .:.||.||:|      :||.:    |..:|||:.|..:.
Mouse   261 -ACGGVLIHTSWVLTAAHCVEGTK--KLTVRLGEYD------LRRRDHWELDLDIKEILVHPNYT 316

  Fly   237 KGSLYNDVAVMLLESPFTLQENIQTVCLPNVGDKFDFDRC----YATGWG-KNKFGKDGEYQ--V 294
            :.|..||:|::.|..|.||.:.|..:||||.|...:..:.    ..|||| ::...|||...  .
Mouse   317 RSSSDNDIALLRLAQPATLSKTIVPICLPNNGLAQELTQAGQETVVTGWGYQSDRIKDGRRNRTF 381

  Fly   295 ILKKVDMPVVPEQQCETNLRETRLGRHFILHDSFICAGGEKD-KDTCKGDGGSPLVCPIAGQKNR 358
            ||..:.:|:|...:|...::.       ::.::.:|||...| :|.|.||.|.|:|....|   .
Mouse   382 ILTFIRIPLVARNECVEVMKN-------VVSENMLCAGIIGDTRDACDGDSGGPMVVFFRG---T 436

  Fly   359 FKSAGIVAWGIGCGEVNIPGVYASVAKLRPWI 390
            :...|:|:||.|||..|..|:|..|.....||
Mouse   437 WFLVGLVSWGEGCGHTNNYGIYTKVGSYLKWI 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	81/250 (32%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	79/248 (32%)
Proc	XP_006525784.1	GLA	50..110	CDD:214503
		EGF_CA	111..155	CDD:238011
		FXa_inhibition	163..198	CDD:373209	10/48 (21%)
		Tryp_SPc	236..470	CDD:238113	83/261 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910