DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and CLIPA5

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_320729.4	Gene:	CLIPA5 / 1280861	VectorBaseID:	AGAP011787	Length:	397	Species:	Anopheles gambiae

Alignment Length:	371	Identity:	180/371 - (48%)
Similarity:	244/371 - (65%)	Gaps:	24/371 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 DSSGSTGSENGGSSSTQYQSCGDQKECVPRWLCANDTINTSGDGIIDIRLGTDAECKNYLDLCCD 115
            :|..|....|..::::...||  ..||||.:||.::.|..:|.|:||||:..:.||.:||:.||
Mosquito    28 ESDESWDIPNSNANTSPNASC--TGECVPYYLCKDNKIIKNGRGVIDIRVNAEPECPHYLETCC- 89

  Fly   116 LPNKRKDPIFEFKPD---HPEG--------CGYQNPNGVGFKITGAVNQEAEFGEFPWMLAIL-- 167
              |.|.  :.:..|.   .|.|        ||.:|.||:||.:||..:.|:.:||||||:|::
Mosquito    90 --NARS--VLDSPPPGVIKPSGRTEQVRPTCGVRNKNGLGFSVTGVKDGESHYGEFPWMVAVMLS 150

  Fly   168 ----REEGNLNLYECGGALIAPNVVLTAAHCVHNKQPSSIVVRAGEWDTQTQTEIRRHEDRYVKE 228
                ..:..||:|:|||::|||||||||||||.||..:.:::|||||||||:.|:..|::|.|.|
Mosquito   151 SPMDNSDSILNVYQCGGSVIAPNVVLTAAHCVFNKPKTQLLLRAGEWDTQTEHELYMHQNRRVAE 215

  Fly   229 IIYHEQFNKGSLYNDVAVMLLESPFTLQENIQTVCLPNVGDKFDFDRCYATGWGKNKFGKDGEYQ 293
            :|.||.|:..||.||||::.|..||.|.||:|.:|||..|..||:..|:|:||||::|||:|:||
Mosquito   216 VILHEAFDNESLANDVALLTLAEPFQLGENVQPICLPPSGTSFDYQHCFASGWGKDQFGKEGKYQ 280

  Fly   294 VILKKVDMPVVPEQQCETNLRETRLGRHFILHDSFICAGGEKDKDTCKGDGGSPLVCPIAGQKNR 358
            ||||||::||||..:|:..:|..|:|..|:|..||:||||...:|.|:|||||||||||.|....
Mosquito   281 VILKKVELPVVPHAKCQETMRSQRVGNWFVLDQSFLCAGGVAGQDMCRGDGGSPLVCPIPGSPTH 345

  Fly   359 FKSAGIVAWGIGCGEVNIPGVYASVAKLRPWIDAKLKIWSIDPRHY 404
            :..|||||||:||||..|||||..||.||.|||.:|...||..|.|
Mosquito   346 YYQAGIVAWGLGCGEDGIPGVYGDVAFLRDWIDQQLVENSILARDY 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	135/243 (56%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	134/242 (55%)
CLIPA5	XP_320729.4	Tryp_SPc	135..380	CDD:238113	137/244 (56%)
CLIPA5	XP_320729.4	Tryp_SPc	135..377	CDD:214473	134/241 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	339	1.000	Domainoid score	I2953
eggNOG	1	0.900	-	-		E33208_3BM7R
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H122534
Inparanoid	1	1.050	408	1.000	Inparanoid score	I3883
OMA	1	1.010	-	-		QHG27325
OrthoDB	1	1.010	-	-		D23222at50557
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm74813
Panther	1	1.100	-	-	O	PTHR24256
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	1	0.960	-	-
	11	10.940