DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and CLIPA6

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_320728.3	Gene:	CLIPA6 / 1280860	VectorBaseID:	AGAP011789	Length:	427	Species:	Anopheles gambiae

Alignment Length:	415	Identity:	207/415 - (49%)
Similarity:	256/415 - (61%)	Gaps:	37/415 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 AQDSSLDKLISDIFKTDETPKPSSPPPPVVNPKDSSGSTGSENGGSSSTQYQSCGDQKECVPRWL 82
            |.|.|||.||:.:| |...|...:|||....|...:...|.:.|        .||.:..|:.::|
Mosquito    24 ADDLSLDDLINSVF-TTAAPGKGAPPPTSAPPLPPTPDVGVKGG--------PCGGEAVCIQKYL 79

  Fly    83 CANDTINTSGDGIIDIRLGTDAECKNYLDLCC---DL------------PNKRKDPI-----FEF 127
            |:|.  :|||:|:||||...|..|.:||..||   |:            ||....|.     ...
Mosquito    80 CSNS--STSGEGLIDIRFSDDNPCVDYLLQCCFEEDIIQPPPPVPPAPGPNPGPGPSPGPGPAPI 142

  Fly   128 KPDHPEG-CGYQNPNGVGFKITGAVNQEAEFGEFPWMLAILREE---GNL--NLYECGGALIAPN 186
            .|..||. ||.:|.:|:||:|||:.|.|||:||||||:|||:.|   |.|  |:|.|||:||...
Mosquito   143 PPPMPESRCGRRNVDGIGFRITGSKNSEAEYGEFPWMVAILKTEEVLGQLRENVYTCGGSLIHRQ 207

  Fly   187 VVLTAAHCVHNKQPSSIVVRAGEWDTQTQTEIRRHEDRYVKEIIYHEQFNKGSLYNDVAVMLLES 251
            ||||.||||.|||||.:.||.|||||||:.||..|:||.|.||:.|..:.||.|:||||::.|.:
Mosquito   208 VVLTGAHCVQNKQPSQLKVRVGEWDTQTKNEIYPHQDRSVVEIVVHPDYYKGGLHNDVALLFLNA 272

  Fly   252 PFTLQENIQTVCLPNVGDKFDFDRCYATGWGKNKFGKDGEYQVILKKVDMPVVPEQQCETNLRET 316
            |....|:|||||||.....|:.:.|:|:||||:.|||.|.|||||||:|:||||..||:|.||.|
Mosquito   273 PVEPNESIQTVCLPPQDMAFNHETCFASGWGKDVFGKAGTYQVILKKIDLPVVPNDQCQTALRTT 337

  Fly   317 RLGRHFILHDSFICAGGEKDKDTCKGDGGSPLVCPIAGQKNRFKSAGIVAWGIGCGEVNIPGVYA 381
            |||..|.||.|||||||...||||||||||||||||....:.:...|:|||||||||..||||||
Mosquito   338 RLGPKFNLHKSFICAGGVPGKDTCKGDGGSPLVCPIPNSPHHYYQTGLVAWGIGCGENGIPGVYA 402

  Fly   382 SVAKLRPWIDAKLKIWSIDPRHYTP 406
            :|||.|.|||..:...:.....|||
Mosquito   403 NVAKFRGWIDQHMVQRNFGADSYTP 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	149/242 (62%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	148/241 (61%)
CLIPA6	XP_320728.3	Tryp_SPc	162..411	CDD:214473	152/248 (61%)
CLIPA6	XP_320728.3	Tryp_SPc	169..414	CDD:238113	151/244 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BM7R
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H122534
Inparanoid	1	1.050	408	1.000	Inparanoid score	I3883
OMA	1	1.010	-	-		QHG27325
OrthoDB	1	1.010	-	-		D23222at50557
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm74813
Panther	1	1.100	-	-	O	PTHR24256
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	10	9.980