DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and CLIPA7

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_320723.2	Gene:	CLIPA7 / 1280856	VectorBaseID:	AGAP011792	Length:	821	Species:	Anopheles gambiae

Alignment Length:	378	Identity:	178/378 - (47%)
Similarity:	233/378 - (61%)	Gaps:	41/378 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 KPSSPPPPVVNPKDSSGSTGSENGGSSSTQ-------YQSCGDQKECVPRWLCANDTINTSGDGI 95
            |.:||.|    .|...|: |..:||....:       |...|..|...|..|..: .|:|.
Mosquito   471 KEASPTP----GKQPDGA-GQHHGGPGGAKHPDTGGGYNQGGGVKGTQPAALITH-PIDTD---- 525

  Fly    96 IDIRLGTDAECKNYLDLCCDLPNKRKDPIFEFKPDHPEGCGYQNPNGVGFKITGAVNQEAEFGEF 160
               ::||..:  |.||....:|.|               ||.:|.:||||:|||..:.|:|:|||
Mosquito   526 ---KVGTGTQ--NPLDKTVSVPQK---------------CGLRNVDGVGFRITGDNDGESEYGEF 570

  Fly   161 PWMLAILREEGNL----NLYECGGALIAPNVVLTAAHCVHNKQPSSIVVRAGEWDTQTQTEIRRH 221
            |||:|||:||..|    |:|:|||:||.|:|||||||||.|::...:.||.|||||||:.|:..:
Mosquito   571 PWMVAILKEEKALDQVINVYQCGGSLIHPSVVLTAAHCVQNRKIEEVKVRLGEWDTQTKNEMFDY 635

  Fly   222 EDRYVKEIIYHEQFNKGSLYNDVAVMLLESPFTLQENIQTVCLPNVGDKFDFDRCYATGWGKNKF 286
            :||.|.||:.|.:..||.|:||||::.|:.|..|.|.:.|:|||.....||..||:|:||||:.|
Mosquito   636 QDRNVVEIVSHAEIYKGGLFNDVALLFLDKPADLMETVNTICLPPANHNFDMSRCFASGWGKDVF 700

  Fly   287 GKDGEYQVILKKVDMPVVPEQQCETNLRETRLGRHFILHDSFICAGGEKDKDTCKGDGGSPLVCP 351
            ||.|.|||||||:::|::|.::|:..||.|||||.|.||.|||||||||.:|||||||||||:||
Mosquito   701 GKQGTYQVILKKIELPIMPNEECQKALRTTRLGRRFKLHSSFICAGGEKGRDTCKGDGGSPLICP 765

  Fly   352 IAGQKNRFKSAGIVAWGIGCGEVNIPGVYASVAKLRPWIDAKLKIWSIDPRHY 404
            |.|..|.:..||:|||||||||..|||||.:|...|.|||..|:..:|....|
Mosquito   766 IPGSVNHYYQAGMVAWGIGCGEDGIPGVYVNVPMFRGWIDDHLRQRNITDSFY 818

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	140/241 (58%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	139/240 (58%)
CLIPA7	XP_320723.2	BAT2_N	<406..487	CDD:284431	7/20 (35%)
		Tryp_SPc	556..804	CDD:214473	142/247 (57%)
		Tryp_SPc	564..807	CDD:238113	142/242 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	339	1.000	Domainoid score	I2953
eggNOG	1	0.900	-	-		E33208_3BM7R
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H122534
Inparanoid	1	1.050	408	1.000	Inparanoid score	I3883
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D23222at50557
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24256
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.970