DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and AgaP_AGAP011793

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_320722.4	Gene:	AgaP_AGAP011793 / 1280855	VectorBaseID:	AGAP011793	Length:	426	Species:	Anopheles gambiae

Alignment Length:	394	Identity:	167/394 - (42%)
Similarity:	223/394 - (56%)	Gaps:	65/394 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 STQYQSCGDQKECVPRWLCANDTINTSGDGIIDIRLGTDAECKNYLDLCCDLP----NKRKDPIF 125
            |.:.:.| |..||||...|.:..:...|..:|.:||..:.|| :||:.||..|    ::.:|.:.
Mosquito    21 SEKAKPC-DGGECVPVTKCKSGELEDHGAYVISLRLNPEDEC-SYLETCCPYPKDEDDESRDELG 83

  Fly   126 EF----------------------------------------KPDH---------------PEGC 135
            |.                                        |.::               |:.|
Mosquito    84 ELLKAPATGNGAGEALNVAAEQVPSVAAQRANLLSSSGANNVKSENLKAATNRPPTASATGPQTC 148

  Fly   136 GYQNPNGVGFKITGAVNQEAEFGEFPWMLAILREEGNL----NLYECGGALIAPNVVLTAAHCVH 196
            |.:|.|||.|:||...:.|:|:||||||.|||.|:..|    |.|.|||:||.|:|:|||||||.
Mosquito   149 GVRNSNGVQFRITDDSDGESEYGEFPWMAAILEEQKALDQIINTYMCGGSLIHPSVILTAAHCVQ 213

  Fly   197 NKQPSSIVVRAGEWDTQTQTEIRRHEDRYVKEIIYHEQFNKGSLYNDVAVMLLESPFTLQENIQT 261
            |...:::.||.|||||::..|...|:||.|.||.:||||...:..|:||::.|:.|..|.|.:.|
Mosquito   214 NITITALKVRLGEWDTRSWKEPFPHQDRRVVEIAFHEQFFAPAALNNVALLFLDKPVELMETVNT 278

  Fly   262 VCLPNVGDKFDFDRCYATGWGKNKFGKDGEYQVILKKVDMPVVPEQQCETNLRETRLGRHFILHD 326
            :|||.....||..||.|:||||:.||.:|.:|.|||||::|::|...|:..||.|||||.|.||:
Mosquito   279 ICLPPANYTFDPVRCVASGWGKDVFGNEGMFQAILKKVELPLMPRGACQRALRMTRLGRRFKLHE 343

  Fly   327 SFICAGGEKDKDTCKGDGGSPLVCPIAGQKNRFKSAGIVAWGIGCGEVNIPGVYASVAKLRPWID 391
            ||:||||||.:|||||||||||||||.|..|.:..|.||||||.||...:||||.:||..|.|||
Mosquito   344 SFLCAGGEKGRDTCKGDGGSPLVCPIPGVANGYYQASIVAWGINCGIEGVPGVYVNVALFREWID 408

  Fly   392 AKLK 395
            .:|:
Mosquito   409 EQLR 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	132/241 (55%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	131/240 (55%)
AgaP_AGAP011793	XP_320722.4	Tryp_SPc	167..410	CDD:238113	134/242 (55%)
AgaP_AGAP011793	XP_320722.4	Tryp_SPc	167..407	CDD:214473	131/239 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BM7R
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H122534
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG27325
OrthoDB	1	1.010	-	-		D23222at50557
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	7	6.830