DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and AgaP_AGAP008911

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_319658.4	Gene:	AgaP_AGAP008911 / 1279878	VectorBaseID:	AGAP008911	Length:	579	Species:	Anopheles gambiae

Alignment Length:	274	Identity:	76/274 - (27%)
Similarity:	120/274 - (43%)	Gaps:	45/274 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 NQEAEFGEFPWMLAILREEGNLNLYECGGALIAPNVVLTAAHCVHNKQPSSIV------VRAGEW 210
            |.:|..|.:||..||...:|....|.|||:::....:|||::||:.  ||.::      |..|:.
Mosquito    44 NGDAIAGHWPWYAAIYHRKGEKQEYACGGSILDETTILTASNCVYT--PSGVISAALVTVHVGQI 106

  Fly   211 DTQTQTEIRRHEDRYVKEIIYHEQFNKGSLYNDVAVMLLESPFTL-QENIQTVCLPNVGDKFDFD 274
            ..:..:...:..|  |:||:.|..|::.|..||:|::.|.:..|| .|.:|.|||      :..|
Mosquito   107 HPKQASAYAQMYD--VREIVVHPGFSEASTINDIALIKLTASITLTTEYVQPVCL------WTMD 163

  Fly   275 RCYATGWGKN----KFGKDGEYQVI----LKKVDMPVVPEQQCETNLRETRLGRHFILHDSFICA 331
            .......|:|    .||.:....|:    |::..:.||..|.|..: .....|.|..: ::|...
Mosquito   164 SALELIVGRNGTVVGFGPNERRDVVSGEQLQQATIGVVDPQTCIAS-DPAIFGTHLPV-ETFCGK 226

  Fly   332 GGEKDKDTCKGDGGSPLVCPIAGQKNRFKSAGIVAW--------GIGCGEVNIPGVYASVAKLRP 388
            |.:.....|.||.|..|...::||   :...|:||.        |: |..:... ||..|||...
Mosquito   227 GLQNGAGACNGDSGDGLFFEVSGQ---WFVRGLVARLQPVRESDGL-CDPLQYT-VYTDVAKYVD 286

  Fly   389 WIDAKLKIWSIDPR 402
            ||..     .:|||
Mosquito   287 WIKR-----YVDPR 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	71/260 (27%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	70/259 (27%)
AgaP_AGAP008911	XP_319658.4	Tryp_SPc	359..573	CDD:304450
		Tryp_SPc	46..290	CDD:238113	72/260 (28%)
		Tryp_SPc	46..288	CDD:214473	70/258 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910