DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and AgaP_AGAP003960

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_318412.5	Gene:	AgaP_AGAP003960 / 1278781	VectorBaseID:	AGAP003960	Length:	579	Species:	Anopheles gambiae

Alignment Length:	277	Identity:	71/277 - (25%)
Similarity:	118/277 - (42%)	Gaps:	31/277 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 EGCGYQNPNGVGFKITGAVNQEAEFGEFPWMLAILREEGNLNLYECGGALIAPNVVLTAAHCVHN 197
            :.||.:..  |...||..:  |::.|::||.:|:.........|.|||:::..|.:||||||:..
Mosquito    27 QNCGKRKQ--VNLLITNGL--ESKEGDWPWHVALFHNNRRSFEYACGGSILDQNTILTAAHCLWL 87

  Fly   198 KQ----PSSIVVRAGEWDTQTQTEIRRHEDRYVKEIIYHEQFNKGSLYNDVAVMLLESPFTLQEN 258
            ..    ...::|:.|....:..:...|..:.|  |:|.|.::|...:.||:|::.|.:..|....
Mosquito    88 SNGLIAKERLLVQVGRSRLRVASIHARDHEAY--ELIVHPKYNVNQIANDIALIKLATDITFTNF 150

  Fly   259 IQTVCLPNVGDKFDFDRCYAT-----GWGKNKFGKDGEYQVILKKVDMPVVPEQQCETNLRETRL 318
            :|.:||.|.||  |......|     |:|.::.....:   .|::..:|||....|..:.||...
Mosquito   151 VQPICLWNRGD--DQSSIVGTLGTVIGFGYDETDNPTD---TLREARLPVVSAIDCIQSNREAFA 210

  Fly   319 GRHFILHDSFICAGGEKDKDTCKGDGGSPLVCPIAGQKNRFKSAGIVAWGIGCGEVNIPG----- 378
            .:   |.....|||.......|.||.|..|   .....|.:...|:|::.....:..|..
Mosquito   211 TQ---LTSDMFCAGYRNGTSPCNGDSGGGL---FFNFNNVWYIRGLVSFTKPRQDTTICDTKEYT 269

  Fly   379 VYASVAKLRPWIDAKLK 395
            |:..|||...||:..|:
Mosquito   270 VFTDVAKYLRWIEQYLR 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	64/251 (25%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	63/250 (25%)
AgaP_AGAP003960	XP_318412.5	Tryp_SPc	39..283	CDD:238113	67/258 (26%)
		Tryp_SPc	39..281	CDD:214473	65/256 (25%)
		Tryp_SPc	331..573	CDD:214473
		Tryp_SPc	331..573	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910