DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and AgaP_AGAP011427

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_317876.4	Gene:	AgaP_AGAP011427 / 1278263	VectorBaseID:	AGAP011427	Length:	868	Species:	Anopheles gambiae

Alignment Length:	263	Identity:	77/263 - (29%)
Similarity:	114/263 - (43%)	Gaps:	31/263 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   147 ITGAVNQEAEFGEFPWMLAI--LREEGNLNLYECGGALIAPNVVLTAAHCV---HNKQPSSIVVR 206
            |.|.....|..|||..|.||  .|.|.|:: |.|||:||....|||||||.   .|..|.:  ||
Mosquito    17 IQGLGGTRAYQGEFQHMAAIGWTRPENNID-YLCGGSLITLKFVLTAAHCAVDYANVPPDT--VR 78

  Fly   207 AGEWDTQTQTEIRRHEDRYVKEIIYHEQFNKGSLYNDVAVMLLESPFTLQENIQTVCL------- 264
            .|:.|..:..:....:...:...|.|.|:.:...|.|:|::.|.:.....:.:...|:
Mosquito    79 LGDTDLASTDDDESAQQIPIARFIKHPQYRESRKYYDIALVELANVVDADDAVCVACVWREPEAP 143

  Fly   265 PNVGDKFDFDRCYATGWGKNKFGKDGEYQVILKKVDMPVVPEQQCETNLRETRLGRHFILHDSFI 329
            .|:.|        |.|:|...||:  :....|:||.:..:...||...:...|......|.|..:
Mosquito   144 TNLLD--------AVGFGALGFGE--KLSPTLQKVQLRALSAVQCAERIPANRRQMPEGLRDDQL 198

  Fly   330 CAGGEKDKDTCKGDGGSPL---VCPIAGQKNRFKSAGIVAWGIGCGEVNIPGVYASVAKLRPWID 391
            || ..|..|||:||.|.||   ...:.|:.... ..|:|::|..|.| ...|||..|:....||:
Mosquito   199 CA-HSKTMDTCEGDSGGPLQTEALDVFGETYPL-VVGVVSFGTPCIE-GSTGVYTRVSSYVEWIE 260

  Fly   392 AKL 394
            .::
Mosquito   261 KEV 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	74/252 (29%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	73/251 (29%)
AgaP_AGAP011427	XP_317876.4	Tryp_SPc	21..261	CDD:238113	75/255 (29%)
		Tryp_SPc	21..259	CDD:214473	73/253 (29%)
		Tryp_SPc	306..546	CDD:238113
		Tryp_SPc	306..544	CDD:214473
		Tryp_SPc	625..862	CDD:214473
		Tryp_SPc	630..864	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910