DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and SCRASP2

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_316661.5	Gene:	SCRASP2 / 1277217	VectorBaseID:	AGAP006631	Length:	1343	Species:	Anopheles gambiae

Alignment Length:	304	Identity:	101/304 - (33%)
Similarity:	150/304 - (49%)	Gaps:	33/304 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 CDLPNKRKDPIFEFKPDHPEGCGYQNPNGVGFKITGAV--NQEAEFGEFPWMLAILREEGNLNLY 176
            ||: |.|. |:.|....:.| || :..|...||.|..:  ...:..|::|::.|||  .|...::
Mosquito  1047 CDI-NSRY-PVAELTCSNFE-CG-KVRNRKYFKATKRIVGGSTSNPGDWPFIAAIL--GGPEEVF 1105

  Fly   177 ECGGALIAPNVVLTAAHCVHNKQPSSIVVRAGEWDTQTQTEIRRHEDRY-----VKEIIYHEQFN 236
            .|.|.|||...||||:||:.|...|..:....:|..|.....||....|     ||.:|.|..:|
Mosquito  1106 YCAGVLIADQWVLTASHCIGNSPTSHTMRNVNDWTIQLGITRRRSHTYYGQKVKVKTVIPHPMYN 1170

  Fly   237 KGSLY----NDVAVMLLESPFTLQENIQTVCL--PNVGDKFDFDRCYATGWGK----NKFGKDGE 291
               |:    ||:|:..|.:.....|::..|||  |::.:......|...||||    |.......
Mosquito  1171 ---LHIPHDNDIALFQLATRVAFHEHLLPVCLPPPHIRELPTGINCTVVGWGKREERNSTPNGAS 1232

  Fly   292 YQVILKKVDMPVVPEQQCETNLRETRLGRHFILHDSFICAG-GEKDKDTCKGDGGSPLVCPIAGQ 355
            |:..|.:|::|:|..:.| .:..||     |.:.:..|||| .|..:|.|:||.|.||:||...:
Mosquito  1233 YEPTLNEVNVPIVSRELC-IDWLET-----FNVTEGMICAGYQEGGRDACQGDSGGPLLCPYPNE 1291

  Fly   356 KNRFKSAGIVAWGIGCGEVNIPGVYASVAKLRPWIDAKLKIWSI 399
            |:|:...|||:||:.|....:|||||:|.|..|||.|::...|:
Mosquito  1292 KDRWFVGGIVSWGVRCAHPKLPGVYANVPKFIPWILAQINNHSV 1335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	85/253 (34%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	84/252 (33%)
SCRASP2	XP_316661.5	Fz	753..857	CDD:279700
		LDLa	889..918	CDD:238060
		LDLa	921..955	CDD:294076
		SRCR_2	956..>1011	CDD:295335
		Tryp_SPc	1079..1326	CDD:214473	84/257 (33%)
		Tryp_SPc	1080..1326	CDD:238113	84/256 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910