DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5390 and AgaP_AGAP010545

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_314514.4	Gene:	AgaP_AGAP010545 / 1275276	VectorBaseID:	AGAP010545	Length:	876	Species:	Anopheles gambiae

Alignment Length:	273	Identity:	79/273 - (28%)
Similarity:	129/273 - (47%)	Gaps:	41/273 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 YQNPN----GVGFKITGAVNQEAEFGEFPWMLAILREEGNLNLYECGGALIAPNVVLTAAHCVHN 197
            |::.|    |..|.....:.:.|..|...|    .:.:|.: ::.|||:||..|.::|||||..|
Mosquito     7 YRHGNTGIVGPAFAKPAFLTEFAHIGAIGW----TQPDGKI-IWGCGGSLIWNNFIITAAHCTAN 66

  Fly   198 -KQPSSIVVRAGEWDTQTQTEIRRHEDRYVKE-----IIYHEQFNKGSLYNDVAVMLLESPFTLQ 256
             ...|..|||.|:.:..:.     .:|||.::     ||.|.:::..:.|.|:|:|.|::..::.
Mosquito    67 DDNVSPDVVRFGDLNIYSD-----EDDRYAQQLTIVSIIRHPKYSFSARYYDIALMKLDNNVSVH 126

  Fly   257 ENIQTVCLPNVGDKFDFDRCYATGWGKNKFGKDGEYQVILKKVDMPVVPEQQC-----ETNLRET 316
            |.:...|| .:..:..|....:.|||:..||:..  ..||.|:.:..:..:.|     .|.:|..
Mosquito   127 ETVAPACL-WLDKEVRFKELESAGWGQTGFGESP--TPILLKITLKPMSNENCTEHYTSTTVRGL 188

  Fly   317 RLGRHFILHDSFICAGGEKDKDTCKGDGGSPLVCPIAGQKNRFK----SAGIVAWGIGCGEVNIP 377
            :.|    |....||||..| .|||.||.|.||...:   ::.:|    ..|:.::|..||:.: |
Mosquito   189 QRG----LDQHHICAGDAK-MDTCLGDSGGPLHIRL---QHNYKVTPFLVGLTSFGRPCGQSH-P 244

  Fly   378 GVYASVAKLRPWI 390
            |||..:|..|.||
Mosquito   245 GVYTRIAPFRSWI 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	75/253 (30%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	73/251 (29%)
AgaP_AGAP010545	XP_314514.4	Trypsin	21..257	CDD:278516	73/257 (28%)
		Tryp_SPc	47..260	CDD:238113	71/228 (31%)
		Tryp_SPc	336..544	CDD:304450
		Tryp_SPc	677..867	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910