DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and AgaP_AGAP005072

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_313947.4	Gene:	AgaP_AGAP005072 / 1274755	VectorBaseID:	AGAP005072	Length:	857	Species:	Anopheles gambiae

Alignment Length:	275	Identity:	77/275 - (28%)
Similarity:	115/275 - (41%)	Gaps:	69/275 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 AEFGEFPWMLAILREEGNLNLYECGGALIAPNVVLTAAHCVHNKQP----SSIVVRA-------- 207
            |:.|.:||...:.    :||.|:||..||....||||:|||:|...    |..:||.
Mosquito    66 ADEGHWPWHGGLF----HLNDYQCGCTLINELFVLTASHCVYNSDTGYKISEKLVRVRLGMHRLS 126

  Fly   208 --GEWDTQTQTEIRRHEDRYVKEIIYHEQFNKGSLYNDVAVMLLESPFTLQENIQTVCL---PNV 267
              |....||.|         |::||.|.:|...:..:|||::.|.........||.|||   .::
Mosquito   127 ANGSSAVQTYT---------VQKIIPHSKFVPNTHKHDVALLRLNGTVKFTNYIQPVCLDLTESI 182

  Fly   268 GDKFDFDRCYAT--GWG---KNKFGKDGEYQVILKKVDMPVVPEQQC-ETNLRETRLGRHFILHD 326
            ..::..| .|.|  |||   ||:....      |.|.::|:|....| |:|  ....||  :::.
Mosquito   183 WVEYLAD-VYGTVVGWGLTEKNRISDQ------LLKAELPIVRYTDCVESN--PDLYGR--LIYS 236

  Fly   327 SFICAGGEKDKDTCKGDGGSPLVCPIAGQKNRFKSAGIVAW-GIGCGE-----------VNIPGV 379
            ...|||.......|.||.|..:   ...::||:...|:|:: ||..|.           :|:| .
Mosquito   237 GMYCAGILNGTSPCNGDSGGGM---YIFRENRWFLRGVVSFSGIREGTNYCDSFSYVVFMNVP-Y 297

  Fly   380 YASVAKLRPWIDAKL 394
            ||.      ||..::
Mosquito   298 YAK------WIGTEV 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	76/270 (28%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	75/269 (28%)
AgaP_AGAP005072	XP_313947.4	Tryp_SPc	59..302	CDD:214473	75/269 (28%)
		Tryp_SPc	60..302	CDD:238113	75/269 (28%)
		IG_like	373..447	CDD:214653
		IGc2	377..436	CDD:197706
		LamG	451..600	CDD:238058
		LamG	673..826	CDD:238058
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910