DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and AgaP_AGAP004570

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_313874.5	Gene:	AgaP_AGAP004570 / 1274709	VectorBaseID:	AGAP004570	Length:	259	Species:	Anopheles gambiae

Alignment Length:	263	Identity:	85/263 - (32%)
Similarity:	131/263 - (49%)	Gaps:	34/263 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 FKITGAVNQEAEF--------GEFPWMLAILREEGNLNLYECGGALIAPNVVLTAAHCVHNKQPS 201
            |...||.|||...        .::|| ||.|..:|.   :.||.:|:..:.||||||||...:.:
Mosquito    10 FSECGAANQEIRIVGGRPTGVNQYPW-LARLVYDGQ---FHCGASLLTKDYVLTAAHCVRRLKRN 70

  Fly   202 SIVVRAGEWD----TQTQTEIRRHEDRYVKEIIYHEQFNKGSLYNDVAVMLLESPFTLQENIQTV 262
            .|.|..|::|    ::|...:|.     |..||.|..|::.|..:|:|::.|..|....:.|:.|
Mosquito    71 KIRVILGDYDQFVASETPAIMRA-----VTAIIRHRSFDQNSYNHDIALLKLRKPVEFTKTIRPV 130

  Fly   263 CLPNVGDKFDFDRCYATGWGKNKFGKDGEYQVILKKVDMPVVPEQQCET-NLRETRLGRHFILHD 326
            |||....:.........|||:...|  |....:::.||:|::...||.: ..|.:|      :..
Mosquito   131 CLPKERSEPAGQLGTVVGWGRTSEG--GTLPALVQHVDVPILTLDQCRSMKYRASR------ITS 187

  Fly   327 SFICAGGEKDKDTCKGDGGSPLVCPIAGQKNRFKSAGIVAWGIGCGEVNIPGVYASVAKLRPWID 391
            :.:|||..| :|:|:||.|.||   :....::.:..|||:||:|||....||||..||:..||:.
Mosquito   188 NMLCAGKGK-QDSCQGDSGGPL---LVRNGDKHEIVGIVSWGVGCGRAGYPGVYTRVARYLPWLR 248

  Fly   392 AKL 394
            |.|
Mosquito   249 ANL 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	79/250 (32%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	78/249 (31%)
AgaP_AGAP004570	XP_313874.5	Tryp_SPc	21..246	CDD:214473	75/245 (31%)
AgaP_AGAP004570	XP_313874.5	Tryp_SPc	22..250	CDD:238113	77/248 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	2	1.910