DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and AgaP_AGAP003691

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_313476.4	Gene:	AgaP_AGAP003691 / 1274366	VectorBaseID:	AGAP003691	Length:	831	Species:	Anopheles gambiae

Alignment Length:	342	Identity:	75/342 - (21%)
Similarity:	122/342 - (35%)	Gaps:	92/342 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 IFEFKPDHPEGCGYQNPNGV-------GFKI--TGAVNQEAEFGEFPWMLAILREE--------- 170
            :|.|..|. ||......|.:       |:||  :...::.::|.:|...:|...:.
Mosquito   192 VFNFGSDE-EGLALPVLNYIPWMEEVLGYKILPSECTSKYSDFRDFEDSMASRSDNFVQVQYSKS 255

  Fly   171 --GNLNLYE-----------------CGGALIAPNVVLTAAHCVHNKQPSSIVVRAGEWDTQ--- 213
              .|.|:.:                 |.|:||||..|||||:|:...:.....:..|:::..
Mosquito   256 RLSNTNIEQYKVRIVPKTAETGSKRHCYGSLIAPKFVLTAANCLRQYEVDGYTIEMGQYNVYYPV 320

  Fly   214 TQTEIRRHEDRYVKEIIYHEQFNKGSLYNDVAVMLLESP-FTLQENIQTVCL-PNVGDKFDFDRC 276
            .:..||...:  .|:|.||.:|:..:|.||||::.:..| :|..:.:...|: |  .||...|..
Mosquito   321 QENSIRVRTE--AKKIHYHPEFDAATLANDVALLEIVKPLYTFNKTVLPACIWP--WDKLPVDEY 381

  Fly   277 YATGW------------GKNKFGKDGEYQVILKKVDMPVVPEQQCETNLRETRLGRHFILHDSFI 329
            ...|:            ....|.....|...|.|     ||:.|                    .
Mosquito   382 QTNGYVPFNESDDESVRTNQFFATANVYDECLDK-----VPQHQ--------------------F 421

  Fly   330 CAG--GEKDKDTCKGDGGSPLVCPIAGQKNRFKSA-GIVAWGIGCGEVNIPGVYASVAKLRPWID 391
            |||  ......:|....||.:...:......|... .|.:.|..|| .|:|.||..:|....|||
Mosquito   422 CAGFPTALSPKSCHNSVGSAMSRSLYALGRYFDYIFAINSKGENCG-FNLPTVYTKIAPYVQWID 485

  Fly   392 AKLKIWSI----DPRHY 404
            :.:....:    |.::|
Mosquito   486 SIVHATKVHYEDDTKYY 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	62/285 (22%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	61/284 (21%)
AgaP_AGAP003691	XP_313476.4	Tryp_SPc	80..>152	CDD:304450
		Tryp_SPc	276..484	CDD:214473	56/237 (24%)
		Tryp_SPc	281..487	CDD:304450	59/235 (25%)
		CLIP	506..554	CDD:197829
		Tryp_SPc	600..820	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910