DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and AgaP_AGAP007043

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_001237132.2	Gene:	AgaP_AGAP007043 / 1270058	VectorBaseID:	AGAP007043	Length:	575	Species:	Anopheles gambiae

Alignment Length:	289	Identity:	77/289 - (26%)
Similarity:	132/289 - (45%)	Gaps:	39/289 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 CGYQNPNGVGFKITGAVNQEAEFGEFPWMLAILRE-EGNLNLYECGGALIAPNVVLTAAHCVHNK 198
            ||.:..:.:|....|.:   ||.|::||.:|:... :.....|:|||::|:.:.||:||||:...
Mosquito    36 CGVRRLSPMGLVTKGII---AEPGDWPWHVALFAHMKSEKPAYKCGGSIISQHFVLSAAHCIKEP 97

  Fly   199 QPSSIVVRAG----EWDTQTQTEIRRHEDRYVKEIIYHEQFNKGSLYNDVAVMLLESPFTLQE-N 258
            .|....::||    ..|..|...:..     :.|||.|.::::.:.|||:|:|..:...:... :
Mosquito    98 NPDHYFLKAGIHHLNNDNDTSVVVYN-----LFEIILHPKYDRHTFYNDIALMRPDRAISFASFS 157

  Fly   259 IQTVCLPNVGDKFDFDRCYATGWGKNKFGKDGEYQV--ILKKVDMPVVPEQQCETNLRETRLGRH 321
            |..:||....:....|....:|.... ||.|..:::  .|::..|.|:.:|||...|.|     |
Mosquito   158 IFPICLWPTHNATLIDVLSRSGIAVG-FGFDETHRISETLQQASMKVIEKQQCIEQLPE-----H 216

  Fly   322 --FILHDS-FICA-GGEKDKDTCKGDGGSPLVCPIAGQKNRFKSAGIVAWG----IGCGEVN--- 375
              |:..|: .:|| |.|...:.|.||.|..|   ...:...:...|||:..    :..||..
Mosquito   217 VRFLPQDAGKMCAIGTESGANVCSGDSGGGL---YFAKDQVWYLRGIVSAAARRDLDTGEATCNA 278

  Fly   376 -IPGVYASVAKLRPWIDAKLKIWSIDPRH 403
             :|..|..||:...||:|..::  :|.|:
Mosquito   279 ALPATYTDVAQYTTWINAHQQL--VDQRN 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	69/257 (27%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	68/256 (27%)
AgaP_AGAP007043	XP_001237132.2	Tryp_SPc	50..297	CDD:238113	71/263 (27%)
		Tryp_SPc	50..294	CDD:214473	69/260 (27%)
		Tryp_SPc	330..573	CDD:304450
		Tryp_SPc	330..570	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910