DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and St14

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_446087.1	Gene:	St14 / 114093	RGDID:	69288	Length:	855	Species:	Rattus norvegicus

Alignment Length:	368	Identity:	100/368 - (27%)
Similarity:	161/368 - (43%)	Gaps:	75/368 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 SGSTGSENGGSSSTQYQSCGDQKECVPRWLCANDTINTSGDGIIDIRLGTDAECKNYLDLCC--- 114
            :||....| |....|.|.|..:.:|              |||      ..:|.|.|...:.|
  Rat   527 AGSFKCSN-GKCLPQSQQCNGKDDC--------------GDG------SDEASCDNVNAVSCTKY 570

  Fly   115 ------DLPNKRKDPIFEFKPDHPEG-------CGYQNPNGVGF----KITGAVNQEAEFGEFPW 162
                  .|...:.:|..:.|.|..:|       ||.::     |    ::.|..|  |:.||:||
  Rat   571 TYRCQNGLCLNKGNPECDGKKDCSDGSDEKNCDCGLRS-----FTKQARVVGGTN--ADEGEWPW 628

  Fly   163 MLAI-LREEGNLNLYECGGALIAPNVVLTAAHCVHNKQPSSIVVRAGE--WDT------QTQTEI 218
            .::: ...:|:|    ||.:||:|:.:::||||.   |..:|...:..  |..      |::...
  Rat   629 QVSLHALGQGHL----CGASLISPDWLVSAAHCF---QDETIFKYSDHTMWTAFLGLLDQSKRSA 686

  Fly   219 RRHEDRYVKEIIYHEQFNKGSLYNDVAVMLLESPFTLQENIQTVCLPNVGDKFDFDRC-YATGWG 282
            ...::..:|.||.|..||..:...|:|::.||.|......::.:|||:....|...:. :.||||
  Rat   687 SGVQEHKLKRIITHPSFNDFTFDYDIALLELEKPAEYSTVVRPICLPDNTHVFPAGKAIWVTGWG 751

  Fly   283 KNKFGKDGEYQVILKKVDMPVVPEQQCETNLRETRLGRHFILHDSFICAGGEKDKDTCKGDGGSP 347
            ..|.|..|  .:||:|.::.|:.:..||..|.:....|...:  .|:..|    .|:|:||.|.|
  Rat   752 HTKEGGTG--ALILQKGEIRVINQTTCEELLPQQITPRMMCV--GFLSGG----VDSCQGDSGGP 808

  Fly   348 LVCPIAGQKNRFKSAGIVAWGIGCGEVNIPGVYASVAKLRPWI 390
            |  ....:..|...||:|:||.||.:.|.||||..:.::|.||
  Rat   809 L--SSVEKDGRIFQAGVVSWGEGCAQRNKPGVYTRIPEVRDWI 849

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	75/248 (30%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	73/246 (30%)
St14	NP_446087.1	SEA	88..178	CDD:396113
		CUB	214..332	CDD:238001
		CUB	340..444	CDD:238001
		LDLa	454..486	CDD:238060
		LDLa	492..523	CDD:238060
		LDLa	525..559	CDD:238060	12/52 (23%)
		LDLa	567..602	CDD:238060	6/34 (18%)
		Tryp_SPc	615..852	CDD:238113	77/254 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910