DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and tmprss15

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_031752048.1	Gene:	tmprss15 / 100490249	XenbaseID:	XB-GENE-999987	Length:	994	Species:	Xenopus tropicalis

Alignment Length:	442	Identity:	104/442 - (23%)
Similarity:	183/442 - (41%)	Gaps:	109/442 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 ISDIFKTDETPKPSSPPPPVVNPKDSSG---------STGSENG---GSSSTQYQSCGDQKECVP 79
            :.|:|.|.....       |....||:|         :||...|   ..:||.:| || ..||:|
Frog   579 VKDVFSTTSAMS-------VYFTSDSTGTAKGFLANYTTGLRLGMPEPCNSTSFQ-CG-SGECIP 634

  Fly    80 RWL-------CANDT--------INTSGDGIIDIRLGTD--AECKNYL------DLC--CDLPN- 118
            ...       |.:.|        .|:|..|::..::.::  ..|.::.      |:|  ..|.|
Frog   635 NTAVCDKHRDCDDGTDERHCVRLFNSSMSGLVQFKVQSEWHTACIDHWNEDISNDICHRLGLGNV 699

  Fly   119 ------------------KRKDPIFEFKPDHPEGCGYQN----------------PNGVGFKITG 149
                              :.:|......|.  :.|..|:                |...|.||.|
Frog   700 NLTSAVLSEGNGPFVTLIQVEDGSLSLLPS--DQCANQSVIHIQCQQRECGKRLVPIKSGSKIVG 762

  Fly   150 AVNQEAEFGEFPWMLAILREEGNLNLYECGGALIAPNVVLTAAHCVHNKQ--PSSIVVRAGEWD- 211
              ..:|..|.:||::::...:..    .||.:|:....:::|||||:.:.  ||:...|.|...
Frog   763 --GSDAALGAWPWIVSLYYNDRQ----TCGASLVNQEWLVSAAHCVYGRNLIPSNWKARLGLHTN 821

  Fly   212 -TQTQTEIRRHEDRYVKEIIYHEQFNKGSLYNDVAVMLLESPFTLQENIQTVCLPNVGDKFDFD- 274
             ..||.:|   ..:.:.:|:.:.|:|:.:..:|:.:|.|:......:.||.:|||....:|...
Frog   822 LNLTQPQI---ATQMIDQIVINPQYNRRTKDSDIVMMHLQFKVNYSDYIQPICLPETDQEFSVGI 883

  Fly   275 RCYATGWGKNKFGKDGEYQVILKKVDMPVVPEQQCETNLRETRLGRHFILHDSFICAGGEKDK-D 338
            .|...|||:.:.|  |....||::.::|::...:|:..:.|      :.:.|:.:|.|.|:.. |
Frog   884 NCSIAGWGRTQSG--GPVPNILQEAEIPLISNHKCQQQMPE------YNITDNMVCGGYEEGGID 940

  Fly   339 TCKGDGGSPLVCPIAGQKNRFKSAGIVAWGIGCGEVNIPGVYASVAKLRPWI 390
            ||:||.|.|::|.   |.|.:...|:.::|.||.:.:.||||..|.:...||
Frog   941 TCQGDSGGPMMCQ---QNNEWFLVGVTSFGYGCAQPSRPGVYVRVTEFTNWI 989

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	67/244 (27%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	65/242 (27%)
tmprss15	XP_031752048.1	SEA	36..>103	CDD:396113
		LDLa	157..190	CDD:197566
		CUB	199..305	CDD:238001
		MAM	321..478	CDD:395504
		CUB	501..608	CDD:395345	7/35 (20%)
		LDLa	620..654	CDD:238060	10/35 (29%)
		SR	655..746	CDD:214555	12/92 (13%)
		Tryp_SPc	760..991	CDD:238113	69/250 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910