DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and hgfac

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_002939269.3	Gene:	hgfac / 100485696	XenbaseID:	XB-GENE-940012	Length:	595	Species:	Xenopus tropicalis

Alignment Length:	416	Identity:	112/416 - (26%)
Similarity:	173/416 - (41%)	Gaps:	109/416 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 SSGSTGSENGGSSSTQY------QSC----------GDQKE------CVPRW---LCANDTINTS 91
            |||.|.....|....:|      |||          |.:||      |:| |   :...:.....
Frog   210 SSGKTVCGCRGQYVGKYCNIDVTQSCYDSDNATEYRGIKKETQSGHSCLP-WNSDMLYEEIHTGQ 273

  Fly    92 GDGIIDIRLGTDAECK----NYLDLC------------CDLPNKR---------KDPIFEFKPDH 131
            |...|...||:...|:    :.:..|            |.:|..|         :|.:....|.
Frog   274 GMNFIPKGLGSHPYCRSPDDDEIPWCYLMNDRLVSWEHCSIPKCRDKGRRVIMQEDAVVPAPPK- 337

  Fly   132 PEGCGYQNPNGV---GFKITGAVNQEAEFGEFPWMLAILREEGNLNLYECGGALIAPNVVLTAAH 193
               ||.::...|   | :|.|  ...|..|..||:..|.  .||   |.|.|:||.|..|::|||
Frog   338 ---CGKKHEKRVVARG-RILG--GNSALPGSHPWVAGIY--IGN---YFCAGSLIQPCWVVSAAH 391

  Fly   194 C-VHNKQPSSIVVRAGEWDTQTQTEIRR--HEDRYVKEIIYHEQFNKGSLY----NDVAVMLL-- 249
            | ..:...|.|.|..|:......|::.:  ..:||:       .::|.|::    :|:.::.|
Frog   392 CFADSPSKSKIRVVLGQHFFNQTTDVTQTFEVERYI-------FYDKYSVFKRNEHDIVLIKLKR 449

  Fly   250 -------ESPFTLQENIQTVCLPNVGDKF-DFDRCYATGWGKNKFGKDG-EYQVILKKVDMPVVP 305
                   ::.|     :||:|||:|...| |...|...|||  :..:|. ||...|::..:|:||
Frog   450 INNACAKKTQF-----VQTICLPDVSAPFADDHHCQIAGWG--RMHEDSTEYAQNLQEAIVPLVP 507

  Fly   306 EQQCETNLRETRLGRHFILHDSFICAG-GEKDKDTCKGDGGSPLVCPIAGQKNRFKSA-GIVAWG 368
            :.:|.:   ....|..  :.::..||| .:...|:|:||.|.||.|    :|::.... |||:||
Frog   508 DNKCSS---PEIYGAE--ISENMFCAGYFDCTIDSCQGDSGGPLAC----EKDKISYLWGIVSWG 563

  Fly   369 IGCGEVNIPGVYASVAKLRPWIDAKL 394
            .|||..|.||||..|:....||:.|:
Frog   564 EGCGNHNKPGVYTKVSNYVDWINRKI 589

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	78/257 (30%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	77/256 (30%)
hgfac	XP_002939269.3	FN2	52..98	CDD:238019
		EGF_CA	109..145	CDD:238011
		FN1	147..185	CDD:238018
		KR	235..319	CDD:294073	15/84 (18%)
		Tryp_SPc	351..585	CDD:214473	79/263 (30%)
		Tryp_SPc	352..588	CDD:238113	81/265 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910