DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5390 and tmprss3a

DIOPT Version :9

Sequence 1:	NP_001285802.1	Gene:	CG5390 / 34383	FlyBaseID:	FBgn0032213	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_021334565.1	Gene:	tmprss3a / 100000148	ZFINID:	ZDB-GENE-070912-70	Length:	543	Species:	Danio rerio

Alignment Length:	253	Identity:	83/253 - (32%)
Similarity:	130/253 - (51%)	Gaps:	23/253 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 KITGAVNQEAEFGEFPWMLAILREEGNLNLYECGGALIAPNVVLTAAHCVHN-KQPSSIVVRAGE 209
            :|.|. |..|| |:|||.:::..:..:|    |||::|....:|||||||:. ..|...:|.||
Zfish   297 RIVGG-NLSAE-GQFPWQVSLHFQNEHL----CGGSIITSRWILTAAHCVYGIAYPMYWMVYAG- 354

  Fly   210 WDTQTQTEIRRHEDRYVKEIIYHEQFNKGSLYNDVAVMLLESPFTLQENIQTVCLPNVGDKF-DF 273
               .|:..:...:...|::||||.::....|.:|:|:|.|..|.|....::.:||||.|::| |.
Zfish   355 ---LTELPLNAVKAFAVEKIIYHSRYRPKGLDHDIALMKLAQPLTFNGMVEPICLPNFGEQFEDG 416

  Fly   274 DRCYATGWGKNKFGKDGEYQVILKKVDMPVVPEQQCETNLRETRLGRHFILHDSFICAGG-EKDK 337
            ..|:.:|||..:.|  |:..|......:|::..:.|  :..|...|   .|....||||. :...
Zfish   417 KMCWISGWGATEDG--GDASVSQHCASVPLISNKAC--SQPEVYQG---YLTAGMICAGYLDGGT 474

  Fly   338 DTCKGDGGSPLVCPIAGQKNRFKSAGIVAWGIGCGEVNIPGVYASVAKLRPWIDAKLK 395
            |:|:||.|.||.|.   ..:.:|..|..:||.||.|.|.||||..:.:...||..:::
Zfish   475 DSCQGDSGGPLACE---DSSIWKLVGATSWGQGCAEKNKPGVYTRITQSLTWIHLQME 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	79/240 (33%)
CG5390	NP_001285802.1	Tryp_SPc	153..390	CDD:214473	78/239 (33%)
tmprss3a	XP_021334565.1	LDLa	154..186	CDD:238060
		SRCR_2	191..292	CDD:317845
		Tryp_SPc	298..525	CDD:238113	82/246 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910