DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CYLD and AT4G34670

DIOPT Version :9

Sequence 1:	NP_609371.2	Gene:	CYLD / 34380	FlyBaseID:	FBgn0032210	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_195193.1	Gene:	AT4G34670 / 829619	AraportID:	AT4G34670	Length:	262	Species:	Arabidopsis thaliana

Alignment Length:	171	Identity:	27/171 - (15%)
Similarity:	63/171 - (36%)	Gaps:	43/171 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   264 SDELASICGKFKG-IQGHHNSCYLDATLFSMF--TFTSVFDSILYRRPGPQDIRNYSEVQKVLRD 325
            :|:|.|:..|::. |:.|.:....|.....||  .||.       ||
plant   107 TDKLRSLVKKWQTLIEAHVDVKTTDGYTLRMFCIAFTK-------RR------------------ 146

  Fly   326 EIVNPLRKNVFVRSDRVMKLRELLDQLSSVSGLTCEEKD------PEEFLNSLLSQIMRVEPFLK 384
              .|.:::..:.:|.::.::|..:.::......:|:.|:      ||.....:......:.|.
plant   147 --ANQVKRTCYAQSSQIRQIRRKMSEIMVKEASSCDLKELVAKFIPEAIGREIEKATQGIYPL-- 207

  Fly   385 LSSGQDSYFYQLFVEKDEKLTLPSVQQLFEQSFHSSDIKLK 425
                |:.:..::.:.|..|..|..:.:: ...:.:.|:.:|
plant   208 ----QNVFIRKVKILKAPKFDLGKLMEV-HGDYTAEDVGVK 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CYLD	NP_609371.2	CAP_GLY	143..219	CDD:214997
CYLD	NP_609371.2	Peptidase_C19N	276..631	CDD:239135	23/159 (14%)
AT4G34670	NP_195193.1	Ribosomal_S3Ae	20..221	CDD:395802	23/146 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11830
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100