Protein Alignment Hand and ATOH8

DIOPT Version :10

• Sequence 1: NP_609370.2
• Gene: Hand / 34379
• FlyBaseID: FBgn0032209
• Length: 174
• Species: Drosophila melanogaster
• Sequence 2: XP_011531441.1
• Gene: ATOH8 / 84913
• HGNCID: 24126
• Length: 328
• Species: Homo sapiens
• Alignment Length: 139
• Identity: 37/139 - (26%)
• Similarity: 60/139 - (43%)
• Gaps: 27/139 - (19%)

  Fly    32 SESQVQQQIYNT---------SHLGYVPTSNTRIVKKRNT----ANKKERRRTQSINNAFSYLRE 83
            |.|.:...|||.         ...|....:::.|...:.|    ||.:||.|..:|:.||..||:
Human   191 SYSSISHVIYNNHQDSSASPRKRPGEATAASSEIKALQQTRRLLANARERTRVHTISAAFEALRK 255

  Fly    84 KIPNVPTDTKLSKIKTLKLAILYINYLVNVLDGDLDPKGGFRAELKPVSRKICSEKKHCLKSEIQ 148
            ::|......||||:..|::|..||..|..:.|.|      :.|:...:|...|.::  |.::
Human   256 QVPCYSYGQKLSKLAILRIACNYILSLARLADLD------YSADHSNLSFSECVQR--CTRT--- 309

  Fly   149 NVPLSTKGR 157
               |..:||
Human   310 ---LQAEGR 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hand	NP_609370.2	bHLH_TS_HAND	59..114	CDD:381472	21/58 (36%)
ATOH8	XP_011531441.1	bHLH_TS_ATOH8	224..291	CDD:381427	24/72 (33%)