Protein Alignment Hand and Atoh8

DIOPT Version :10

• Sequence 1: NP_609370.2
• Gene: Hand / 34379
• FlyBaseID: FBgn0032209
• Length: 174
• Species: Drosophila melanogaster
• Sequence 2: NP_722473.1
• Gene: Atoh8 / 71093
• MGIID: 1918343
• Length: 322
• Species: Mus musculus
• Alignment Length: 139
• Identity: 38/139 - (27%)
• Similarity: 60/139 - (43%)
• Gaps: 27/139 - (19%)

  Fly    32 SESQVQQQIYNT---------SHLGYVPTSNTRIVKKRNT----ANKKERRRTQSINNAFSYLRE 83
            |.|.:...|||.         ...|....::|.|...:.|    ||.:||.|..:|:.||..||:
Mouse   192 SYSSISHVIYNNHPDSSASPRKRPGEATAASTEIKALQQTRRLLANARERTRVHTISAAFEALRK 256

  Fly    84 KIPNVPTDTKLSKIKTLKLAILYINYLVNVLDGDLDPKGGFRAELKPVSRKICSEKKHCLKSEIQ 148
            ::|......||||:..|::|..||..|..:.|.|      :.|:...:|...|.::  |.::
Mouse   257 QVPCYSYGQKLSKLAILRIACNYILSLARLADLD------YSADHSNLSFSECVQR--CTRT--- 310

  Fly   149 NVPLSTKGR 157
               |..:||
Mouse   311 ---LQAEGR 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hand	NP_609370.2	bHLH_TS_HAND	59..114	CDD:381472	21/58 (36%)
Atoh8	NP_722473.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..96
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	101..144
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	159..221		6/28 (21%)
		bHLH_TS_ATOH8	225..292	CDD:381427	24/72 (33%)
		Basic motif, degenerate. /evidence=ECO:0000255|PROSITE-ProRule:PRU00981	231..244		5/12 (42%)
		Helix-loop-helix motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00981	245..283		14/37 (38%)