Protein Alignment Hand and TCF21

DIOPT Version :10

• Sequence 1: NP_609370.2
• Gene: Hand / 34379
• FlyBaseID: FBgn0032209
• Length: 174
• Species: Drosophila melanogaster
• Sequence 2: NP_003197.2
• Gene: TCF21 / 6943
• HGNCID: 11632
• Length: 179
• Species: Homo sapiens
• Alignment Length: 157
• Identity: 47/157 - (29%)
• Similarity: 69/157 - (43%)
• Gaps: 22/157 - (14%)

  Fly     8 LTCEYSTMYYNSIYNTSNMFDMKHSESQVQQQIYNTSHLG---YVPTSNTRI--------VKKRN 61
            |.|:...|..|..:.|||....:.|..:..........||   ..||..:.:        ..:||
Human    18 LECDGLKMDSNKEFVTSNESTEESSNCENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRN 82

  Fly    62 TANKKERRRTQSINNAFSYLREKIPNVPTDTKLSKIKTLKLAILYINYLVNVLDGDLDPKG---- 122
            .||.:||.|.:.::.|||.|:..:|.||.||||||:.||:||..||.:|..:|..|....|
Human    83 AANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILANDKYENGYIHP 147

  Fly   123 -----GFRAELKPVS--RKICSEKKHC 142
                 .|....||.|  :::.:..:.|
Human   148 VNLTWPFMVAGKPESDLKEVVTASRLC 174

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hand	NP_609370.2	bHLH_TS_HAND	59..114	CDD:381472	27/54 (50%)
TCF21	NP_003197.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..87		15/66 (23%)
		bHLH_TS_TCF21_capsulin	77..140	CDD:381547	29/62 (47%)