Protein Alignment Hand and Hand2

DIOPT Version :10

• Sequence 1: NP_609370.2
• Gene: Hand / 34379
• FlyBaseID: FBgn0032209
• Length: 174
• Species: Drosophila melanogaster
• Sequence 2: NP_073187.1
• Gene: Hand2 / 64637
• RGDID: 621207
• Length: 217
• Species: Rattus norvegicus
• Alignment Length: 139
• Identity: 76/139 - (54%)
• Similarity: 88/139 - (63%)
• Gaps: 14/139 - (10%)

  Fly    44 SHLGYVP-------TSNTRIVKKRNTANKKERRRTQSINNAFSYLREKIPNVPTDTKLSKIKTLK 101
            ||.|.||       ....|.||:|.|||:||||||||||:||:.|||.|||||.||||||||||:
  Rat    78 SHYGGVPPGAGPPGLGGPRPVKRRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLR 142

  Fly   102 LAILYINYLVNVLDGDLDPKG---GFRAELKPVSRKICSEKK---HCLKSEIQNVPLSTKGRTGW 160
            ||..||.||:::|..| |..|   .|:||:|....|....||   ..|||.:.:....|||||||
  Rat   143 LATSYIAYLMDLLAKD-DQNGEAEAFKAEIKKTDVKEEKRKKELNEILKSTVSSNDKKTKGRTGW 206

  Fly   161 PQDVWASEL 169
            ||.|||.||
  Rat   207 PQHVWALEL 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hand	NP_609370.2	bHLH_TS_HAND	59..114	CDD:381472	40/54 (74%)
Hand2	NP_073187.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..116		20/37 (54%)
		bHLH_TS_HAND2	100..161	CDD:381477	43/61 (70%)