DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Hand and mespaa

DIOPT Version :9

Sequence 1:NP_609370.2 Gene:Hand / 34379 FlyBaseID:FBgn0032209 Length:174 Species:Drosophila melanogaster
Sequence 2:NP_571626.1 Gene:mespaa / 58069 ZFINID:ZDB-GENE-000406-8 Length:223 Species:Danio rerio


Alignment Length:198 Identity:43/198 - (21%)
Similarity:75/198 - (37%) Gaps:59/198 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 TCEYSTMYYNSIYNTSNMFDMKHSESQVQQQIYNTSHLGYVPTSNTRIVK------KRNTANKKE 67
            :|.:|...|:.:   ..:|.....::.||            |...|...|      ||.||:::|
Zfish    47 SCSFSPPAYSLL---PQIFPKSIQKTDVQ------------PPKRTGRPKSKFPGVKRQTASERE 96

  Fly    68 RRRTQSINNAFSYLREKIPN--VPTDTKLSKIKTLKLAILYINYLVNVLDGDLD----------- 119
            :.|.:.:..|..:||..:|.  .|....|:||:||:|||.||:.|.:.|....|           
Zfish    97 KLRMRDLTKALHHLRTFLPASVAPVGKTLTKIETLRLAIQYISCLSDQLGCGEDVEICEAQDEVI 161

  Fly   120 ----------PKGGFRAELKPVSRKI---CSEKKHCLKSEIQNVPLSTKGRTGWPQDVWASELIP 171
                      ......::..|..:.:   |.:.::.::.:..:.|         .||||.|:   
Zfish   162 STSASVFDNFSSASSASQSLPAQQFMSMSCYQTQNPVQGDFHSFP---------AQDVWFSQ--- 214

  Fly   172 EHN 174
            .||
Zfish   215 RHN 217

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HandNP_609370.2 HLH 59..110 CDD:278439 21/52 (40%)
mespaaNP_571626.1 HLH 88..141 CDD:278439 21/52 (40%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4029
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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