DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Hand and ASCL3

DIOPT Version :9

Sequence 1:NP_609370.2 Gene:Hand / 34379 FlyBaseID:FBgn0032209 Length:174 Species:Drosophila melanogaster
Sequence 2:NP_065697.1 Gene:ASCL3 / 56676 HGNCID:740 Length:181 Species:Homo sapiens


Alignment Length:105 Identity:34/105 - (32%)
Similarity:52/105 - (49%) Gaps:18/105 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 YNTSHLGYVPTSNTRIVKKRNTANKKERRRTQSINNAFSYLREKIPNVPTDTKLSKIKTLKLAIL 105
            |......|.|.    ..:||   |::||:|.:.:|..::.||..:|....:.:|||::||:.||.
Human    83 YRGCEYSYGPA----FTRKR---NERERQRVKCVNEGYAQLRHHLPEEYLEKRLSKVETLRAAIK 140

  Fly   106 YINYLVNVLDGDLDPKGGFRAELK----PVSRKICSEKKH 141
            |||||.::|..|       :||.|    .||..|.:...|
Human   141 YINYLQSLLYPD-------KAETKNNPGKVSSMIATTSHH 173

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HandNP_609370.2 HLH 59..110 CDD:278439 20/50 (40%)
ASCL3NP_065697.1 HLH 99..149 CDD:197674 20/49 (41%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4029
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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