Protein Alignment Hand and Ascl5

DIOPT Version :10

• Sequence 1: NP_609370.2
• Gene: Hand / 34379
• FlyBaseID: FBgn0032209
• Length: 174
• Species: Drosophila melanogaster
• Sequence 2: NP_001257538.1
• Gene: Ascl5 / 226439
• MGIID: 2685043
• Length: 188
• Species: Mus musculus
• Alignment Length: 102
• Identity: 32/102 - (31%)
• Similarity: 50/102 - (49%)
• Gaps: 21/102 - (20%)

  Fly    31 HSESQVQQQIYNTSHLG---YVPTSNT----------RIVKKRNTANKKERRRTQSINNAFSYLR 82
            |||..     |..::.|   |||....          ..::||   |::||:|.:.:|..::.||
Mouse    48 HSEPP-----YYDAYTGVFPYVPFPGAFGVYDYPFEPAFIQKR---NERERQRVKCVNEGYARLR 104

  Fly    83 EKIPNVPTDTKLSKIKTLKLAILYINYLVNVLDGDLD 119
            ..:|...|:.:|||::||:.||.||.||..:|....|
Mouse   105 GHLPGALTEKRLSKVETLRAAIRYIKYLQELLSATPD 141

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hand	NP_609370.2	bHLH_TS_HAND	59..114	CDD:381472	22/54 (41%)
Ascl5	NP_001257538.1	bHLH_TS_ASCL5	76..136	CDD:381590	22/62 (35%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00981	80..93		5/15 (33%)
		Helix-loop-helix motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00981	94..132		14/37 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	139..188		1/3 (33%)