Protein Alignment Hand and Twist1

DIOPT Version :10

• Sequence 1: NP_609370.2
• Gene: Hand / 34379
• FlyBaseID: FBgn0032209
• Length: 174
• Species: Drosophila melanogaster
• Sequence 2: NP_035788.1
• Gene: Twist1 / 22160
• MGIID: 98872
• Length: 206
• Species: Mus musculus
• Alignment Length: 76
• Identity: 40/76 - (52%)
• Similarity: 52/76 - (68%)
• Gaps: 2/76 - (2%)

  Fly    47 GYVPTSNTRIVKKRNTANKKERRRTQSINNAFSYLREKIPNVPTDTKLSKIKTLKLAILYINYLV 111
            |..|.|...:..:|..||.:||:||||:|.||:.||:.||.:|:| |||||:|||||..||::|.
Mouse   101 GGSPQSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLY 164

  Fly   112 NVLDGD-LDPK 121
            .||..| ||.|
Mouse   165 QVLQSDELDSK 175

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hand	NP_609370.2	bHLH_TS_HAND	59..114	CDD:381472	31/54 (57%)
Twist1	NP_035788.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..109		3/7 (43%)
		bHLH_TS_TWIST1	102..178	CDD:381418	39/75 (52%)
		Sufficient for transactivation activity	165..195		6/11 (55%)