DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ufd4 and wwtr1

DIOPT Version :9

Sequence 1:	NP_609369.1	Gene:	Ufd4 / 34378	FlyBaseID:	FBgn0032208	Length:	2727	Species:	Drosophila melanogaster
Sequence 2:	NP_001032785.1	Gene:	wwtr1 / 568008	ZFINID:	ZDB-GENE-051101-1	Length:	391	Species:	Danio rerio

Alignment Length:	304	Identity:	55/304 - (18%)
Similarity:	103/304 - (33%)	Gaps:	80/304 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly  1424 KSSSTPSLPEATEKNQNPEGASNQ----TVSADNLAWKQTVETIAENVFASAKTQI--------- 1475
            :.|.|||:.:.:..||....||.|    .:|..||...|......:......:.|:
Zfish   146 RKSMTPSVAQLSLHNQVSNTASIQQRSMALSQPNLVLNQQAHQQQQQHLQQQQQQVPVQVPVQAP 210

  Fly  1476 --ISNQLAMNTSSSREARAKHKESGTNQMHKDNISGPSPLSRELEHISDLSAINNSMPAINSSNV 1538
              .|:|..||.|:.:..:....:  ..||.::.|      .|..|.:.........:| ::|.|:
Zfish   211 QQQSSQPMMNLSAQQHQQKMRLQ--RIQMERERI------QRRQEELMRQEVALRQLP-MDSDNL 266

  Fly  1539 SDLATISENLSLTELSKENICRVLTPSYKPAESVTASQSSSHPDVQSSSPRENDIKNISNIEENN 1603
                                     |...||....|..:.:.|: .|:.|..|     |....:.
Zfish   267 -------------------------PPVAPAIGSPAMSAGNMPN-NSADPFLN-----SGPYHSR 300

  Fly  1604 KMNANNSVNKISKDLLANLRTSNIAGCPPVTQLSTEALEMIDKMRDGVDMIRNMSNSILSTDTFP 1668
            :.:.::.:.               .||..:.....:.|..::.|..|.:|: .:|.::.....||
Zfish   301 EQSTDSGLG---------------LGCYSIPTTPEDFLNNMEDMDTGENMV-PVSMNVPPQSRFP 349

  Fly  1669 -----VPCTNVPVGGKKTPKAQALINPDNANQKQIIVTSEEFPT 1707
                 :|.|||.:|..:......::|    :.:.::..||.|.|
Zfish   350 DFLDSMPGTNVDLGTLEGTDLMPILN----DVESVLNKSEPFLT 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ufd4	NP_609369.1	ANK repeat	393..420	CDD:293786
		ANK	396..509	CDD:238125
		ANK repeat	422..453	CDD:293786
		ANK repeat	455..484	CDD:293786
		F5_F8_type_C	1173..1298	CDD:329041
		MIB_HERC2	1333..1389	CDD:310955
		DamX	1576..>1725	CDD:330571	24/137 (18%)
		HECTc	2265..2725	CDD:238033
wwtr1	NP_001032785.1	WW	115..146	CDD:197736	55/304 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900