Protein Alignment Ufd4 and ube3b

DIOPT Version :9

• Sequence 1: NP_609369.1
• Gene: Ufd4 / 34378
• FlyBaseID: FBgn0032208
• Length: 2727
• Species: Drosophila melanogaster
• Sequence 2: NP_001108154.1
• Gene: ube3b / 556864
• ZFINID: ZDB-GENE-060526-231
• Length: 1069
• Species: Danio rerio
• Alignment Length: 615
• Identity: 128/615 - (20%)
• Similarity: 218/615 - (35%)
• Gaps: 220/615 - (35%)

  Fly  2163 SVLSEDLFISKKITNKLQQQIQDPLVLASNALPNWCENLNQSCPFLFPFETRQLYFNCTSFGASR 2227
            |:|.::|...||....|.|.|                      |.:.|.:.|.|.|        |
Zfish   625 SLLFQELEKGKKRAQLLLQYI----------------------PHVIPHKNRVLLF--------R 659

  Fly  2228 SIVCLQSQRDVTVERQRIPIM-----SPRRDDHEFRIGRLKHERV----KVPRNEDLLMWAMQVM 2283
            :|        ||.|::.:.::     ||.......|..|:..:..    ::|.|
Zfish   660 NI--------VTKEKETLGLVETSSASPHVTHITIRRSRMLEDGYDQLRRLPVN----------- 705

  Fly  2284 KTHCNRKSVLEVEFLDEEG---TGL---GPTLEFYALVAAEIQRSDLCMWLCDDDLGEDTENSTQ 2342
                :.|.|:.|:|:::.|   .|:   |...||...:..::....|              |..:
Zfish   706 ----SIKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKKVFNPAL--------------NLFK 752

  Fly  2343 SAEGNSKPVGYYVNRREHGIFPAPLPQNSEICENVLKYFWFFGVFVAKVLQDMRLVDIPLSTSFL 2407
            :..||.:            ::|:|   .|.|.||.|:.|.|.|..:.|.:.:..:||:|.::.||
Zfish   753 TTSGNER------------LYPSP---TSSIHENHLQLFEFVGKMLGKAMYEGIVVDVPFASFFL 802

  Fly  2408 -QLLCHNKVLSRNLQKVISDRRNGDLSVVSEDSDIVETCTKLLRTDSNKSNAFGGILSLENLKEI 2471
             |:|.|:
Zfish   803 SQVLGHH---------------------------------------------------------- 809

  Fly  2472 DPTRYQFLQEMQNLLLRKQSIEFDDTISAEKKHELINELKLQTQNGLEVSLEDLALTFTYLPSSS 2536
            ..|.|..:.|:.:|     ..||...:::.|::              :..:.||.||.:|  ...
Zfish   810 HSTFYSSIDELPSL-----DSEFYKNLTSIKRY--------------DGDVSDLGLTLSY--DEE 853

  Fly  2537 IYGYTQA-ELLPNGSSVNVTIDNLEAYCELLMNFILQDGIAQQMKAFSDGFNEVFPLKKLAAFTP 2600
            :.|.... ||:|.|.::.||.:|..:|..|:.:|.:...|.:|..||..||..:...:.|..|:.
Zfish   854 VMGQLVCHELIPGGKTMPVTNENKISYIHLMAHFRMHTQIKEQTAAFIRGFRSIINPEWLHMFST 918

  Fly  2601 SEARMMICGEQFPHWSREDIISYTEPKLGYNKDSPGFQRFVNVLL--------SMSGDERKAFLQ 2657
            .|.:.:|.|:.    :..|:....:..:.|.    ||.....|:|        ..:.|||..||:
Zfish   919 PEVQRLISGDN----AEIDLDDLKKHTVYYG----GFHSSHRVILWLWDILSSDFTPDERAMFLK 975

  Fly  2658 FTTGCSSLPPGGLANLHPRLTV------------------------VRKVDAGVGSYPSVNTCVH 2698
            |.|.||..|..|.|.|.|..::                        :||.:.| |..|:.:||.:
Zfish   976 FVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKKEPG-GRLPTSSTCFN 1039

  Fly  2699 YLKLPDYPTEEIMKERLLTA-TKEKGFHLN 2727
            .||||:|..:.|::::|..| :...||.|:
Zfish  1040 LLKLPNYSKKSILRDKLRYAISMNTGFELS 1069

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ufd4	NP_609369.1	ANK repeat	393..420	CDD:293786
		ANK	396..509	CDD:238125
		ANK repeat	422..453	CDD:293786
		ANK repeat	455..484	CDD:293786
		F5_F8_type_C	1173..1298	CDD:329041
		MIB_HERC2	1333..1389	CDD:310955
		DamX	1576..>1725	CDD:330571
		HECTc	2265..2725	CDD:238033	104/504 (21%)
ube3b	NP_001108154.1	IQ	28..50	CDD:197470
		HECTc	683..1067	CDD:238033	106/515 (21%)
		HECTc	708..1066	CDD:214523	101/474 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900