Protein Alignment Ufd4 and CG5087

DIOPT Version :10

• Sequence 1: NP_609369.1
• Gene: Ufd4 / 34378
• FlyBaseID: FBgn0032208
• Length: 2727
• Species: Drosophila melanogaster
• Sequence 2: NP_648279.1
• Gene: CG5087 / 39035
• FlyBaseID: FBgn0035953
• Length: 1078
• Species: Drosophila melanogaster
• Alignment Length: 1040
• Identity: 203/1040 - (19%)
• Similarity: 357/1040 - (34%)
• Gaps: 333/1040 - (32%)

  Fly  1822 VTSLVKLALSSNFHSGL----LSTAQSYPSLSSNNSENIAPSNPSNTSAGQQSASTINHTLTMSL 1882
            :|..::..:..||...|    ||...|.|:|..:..:::.......:|.|          |....
  Fly   238 ITLCLRPLIDGNFSRNLLAKFLSEILSVPALIYHLQQSVPQCLEQFSSMG----------LLKKA 292

  Fly  1883 TSTSSDSEQVSLEDF---LESCRAPALLGDLDDEDDMDEDNDEEENEDEY---EEVGNTLLQV-- 1939
            .|.|.|.:.  .|:|   :...::.|.||::.:..::  |...|..|..|   .|...:||::
  Fly   293 LSISGDVQW--FEEFGTSMPGTKSLAFLGNIVNLFNI--DGQGESKELAYPLLTETTTSLLELIP 353

  Fly  1940 --MVSRNLLTFMDD---------EAMENRLVGVTKRK---SWDDEFVLKRQFSALIPAFDPRPGR 1990
              :.::.:.|...:         |..:|:.|.:.|::   .||.. .:|.....|:.       :
  Fly   354 NTVTTKGVFTQWHELLGWHTPGPEPAQNQNVALIKKQFHMLWDHR-CIKLLLGDLLK-------Q 410

  Fly  1991 TNVNQTSDLEISPLGAELPKPQQSGGPETIEQPLLGLKLRGPGIGGIPEVEIDLSNTDWTIFRAV 2055
            .|:|...        .|...|||                  |.|..:....::.|:|     |.|
  Fly   411 INLNYER--------IEFQSPQQ------------------PSISNLLRRALERSST-----RGV 444

  Fly  2056 QELLQCSQLNKLDKFRKIWEPTYTIVYREVSPEAQESTCLESEEFPQTPDVSSKSGASTLSPNSP 2120
            ..:...|......::||                      |:|.|..|...:.....|: |:..|.
  Fly   445 NLMGVASSKQSKQQWRK----------------------LDSAEVVQVSRICGMYYAA-LNTLSQ 486

  Fly  2121 MHI----GFNVADNNL-------------CSVDDVLELLTQINGLNQSE-----IDSDVKEHGVS 2163
            |.:    |...:||.|             |.:.:.||||.....|.:.:     :..|...|.|:
  Fly   487 MKLDILTGICYSDNVLYDIWLLITSLGPNCGMKEYLELLKSETNLQKPQTAMLMLFCDCMTHYVT 551

  Fly  2164 VLSED--------------LFISKKITNKLQQQIQDPLVLASNALPNWCENLNQSCPFLFPFETR 2214
            :|.|.              :.::..:.|.|.:.|.|.|:..:       :|:.|. |......|.
  Fly   552 ILDEHEMYTEQNPFKLNDYVLLTYFLNNILYKLINDNLLAGA-------KNIVQH-PVFLSLHTL 608

  Fly  2215 QLYFNCTSFGASRSIVCLQSQRDVTVERQRIPIMSPRRDDH----EFRIGRLKHERVKVPRNEDL 2275
            .|              ||. :||.     |.|...|:   |    |.:.....::..|..||..|
  Fly   609 ML--------------CLY-RRDC-----RRPFTPPK---HWLIPEVKPSTFINDLEKAKRNAML 650

  Fly  2276 LMWAMQVMKTHCNRKSVLEVEFLDEEGTGLGPTLEFYALVAAEIQRSDLCMWLCDDDLGED---- 2336
            |:..|..:..|.:|..:.. :|:..|...:|.|..     |....||.|.: :..|.:.||
  Fly   651 LLAKMPHIIPHEDRVKLFR-KFVQNEKAVMGLTES-----ACASPRSALIV-IHRDRIVEDGYRQ 708

  Fly  2337 -TENSTQSAEGNSKPVGYYVNRR---EHGI---------------------------------FP 2364
             ....||:.:|..:.  .::|::   |.||                                 :|
  Fly   709 LAAQPTQALKGVIRV--RFINQQGLHEAGIDQDGVFKEFLEETIKKVFDPSLNLFKTTSDQRLYP 771

  Fly  2365 APLPQNSEICENVLKYFWFFGVFVAKVLQDMRLVDIPLSTSFLQLLCHNKVLSRNLQKVISDRRN 2429
            :|:   |.:.:|.|:.|.|.|..:.|.:.:..:||:|.::.||     :::|.:..|.:.|
  Fly   772 SPI---SYVQDNHLELFEFVGRMLGKAVYEGIVVDVPFASFFL-----SQLLGQTQQALYS---- 824

  Fly  2430 GDLSVVSEDSDIVETCTKLLRTDSNKSNAFGGILSLENLKEIDPTRYQFLQEMQNLLLRKQSIEF 2494
                           |                   ::.|..:|...|:.|..:::.   ||.:
  Fly   825 ---------------C-------------------MDELPSLDNELYRSLTFIKHY---KQDV-- 850

  Fly  2495 DDTISAEKKHELINELKLQTQNGLEVSLEDLALTFTYLPSSSIYG-YTQAELLPNGSSVNVTIDN 2558
                                        .||.|||:.  ...:.| .....|.|.|.:..|...|
  Fly   851 ----------------------------SDLNLTFSV--DQDVMGKIVTLALHPGGKARVVNDHN 885

  Fly  2559 LEAYCELLMNFILQDGIAQQMKAFSDGFNEVFPLKKLAAFTPSEARMMICGEQFPHWSREDIISY 2623
            ...|...:..|.:...|.:|..||:.||..:...:.|:.|:|.|.:.:|.|:..| ...:|:..:
  Fly   886 KLVYIHYMAFFHMNTQIREQTIAFNRGFRSIVNPEWLSLFSPPELQRLISGDTSP-LDLKDLQKH 949

  Fly  2624 TEPKLGYNKDSPGFQRFVNVLL-SMSGDERKAFLQFTTGCSSLPPGGLANLHPRLTV-------- 2679
            |....|::..........::|. ..:.:|||.||:|.|.||..|..|.|:|.|..::
  Fly   950 THYYGGFHDTHQVVCWLWDILAKDFTEEERKLFLKFVTSCSKPPLLGFAHLEPPFSIRCVEVSDD 1014

  Fly  2680 ----------------VRKVDAGVGSYPSVNTCVHYLKLPDYPTEEIMKERLLTA-TKEKGFHLN 2727
                            :||.|. :...|:.:||.:.||||:|..:..::::|..| :...||.|:
  Fly  1015 EDTGDTIGSVIRGFFAIRKKDP-LNRLPTSSTCFNLLKLPNYQKKSTLRDKLRYAVSSNTGFELS 1078

  Fly  2728  2727
              Fly  1079  1078

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ufd4	NP_609369.1	ANKYR	<375..>509	CDD:440430
		ANK repeat	393..420	CDD:293786
		ANK repeat	422..453	CDD:293786
		ANK repeat	455..484	CDD:293786
		Sad1_UNC	1173..1298	CDD:474037
		MIB_HERC2	1333..1390	CDD:461991
		HECTc	2265..2725	CDD:238033	108/527 (20%)
CG5087	NP_648279.1	IQCD	20..50	CDD:467745
		HECTc	694..1076	CDD:238033	92/467 (20%)