Protein Alignment Ufd4 and CG4238

DIOPT Version :9

• Sequence 1: NP_609369.1
• Gene: Ufd4 / 34378
• FlyBaseID: FBgn0032208
• Length: 2727
• Species: Drosophila melanogaster
• Sequence 2: NP_001259896.1
• Gene: CG4238 / 33377
• FlyBaseID: FBgn0031384
• Length: 977
• Species: Drosophila melanogaster
• Alignment Length: 1070
• Identity: 216/1070 - (20%)
• Similarity: 352/1070 - (32%)
• Gaps: 389/1070 - (36%)

  Fly  1748 MSISVPNLTTTSASEVPSTSEVATHTGLLETFAAIARRRTSQGTNIQDNQIMNAEANVNEHGDQN 1812
            :|:||..|.|.:|...||.:..|.|: ||:              .:....::.|...|.......
  Fly   201 VSVSVAGLVTLAAMTQPSLAPEARHS-LLQ--------------YVTGKYLLPANCKVQWDWKDP 250

  Fly  1813 ASGSFLGHSVTSLVKLALSSNFHSGLLSTAQSYP-------------------------SLSSNN 1852
            ||   :|.::..:|:.         .....|.||                         |.:..|
  Fly   251 AS---VGGTMCFVVRF---------FQRNGQPYPICDTDHFFVEVTEGTRKVVTISELGSSTDPN 303

  Fly  1853 SENIAPSNPSNTSAGQQSASTINHTLTMSLTSTSSDSEQVSLEDFLES----------------- 1900
            :.|||....:..:|||...|.        |...|..:....|..||..
  Fly   304 NANIAKVKFTVRTAGQYKISV--------LIGASHIAGSPFLRSFLPGAIDARRSRFIRPASTVI 360

  Fly  1901 -CR-APALLGDLDDEDDMDEDNDEEENEDEYEEVGNTLLQVMVSRNLLTFMDDEAMENRLVGVTK 1963
             |. ||.|:              ..|..||:   ||:.|   ..:|    ..|||::...|.:
  Fly   361 CCAGAPTLM--------------HIEPRDEF---GNSCL---FDQN----QSDEALQGYQVAI-- 399

  Fly  1964 RKSWDDEFV-LKRQFSALIPAFDPRPGRTNVNQTSDLEISPLGAELPKPQQSGGPETIEQPLLGL 2027
               :|...| :::...|::.|:|....|.:|.           |..|:|       |..:.::..
  Fly   400 ---YDLHGVPVEKLQHAIVFAYDKVNSRVSVT-----------ALFPEP-------TCLRAVISY 443

  Fly  2028 KLRGPGIGGIPEVEIDLSNTDWTIFRAVQELLQCSQLNKLDKFRKIWEPTYTIVYREVSPEAQES 2092
            :            :..|.|.|:.|.     :|..|..              |:|::.:: ..:.:
  Fly   444 R------------DQQLPNGDFDII-----VLSSSDT--------------TLVHKNIA-SRKHN 476

  Fly  2093 TCLESEEFPQTPDVSSKSGASTLSPNSPMHIGFNVADNNLCSVDDVLELLTQINGLNQSEI--DS 2155
            .|.|::       :.|..|   :|.|.|..:        ||.|           |..|:.:  ..
  Fly   477 ICYEAK-------LLSIFG---VSKNKPRKV--------LCYV-----------GPKQNSLIFQV 512

  Fly  2156 DVKEHGVSVLSEDLFISKKITN-------------KLQQQIQDPLVLASNALPNWCENLNQSCPF 2207
            .:||   .:|.   ||.|:|..             :|..|:..|:.:..:......|..::....
  Fly   513 TIKE---MILK---FIPKRIATFRLCPSTKFHFLPQLVSQLHGPVFIIDDGAQPKIELASKDRNI 571

  Fly  2208 LFPFETRQLYFNCTSFGASRSIVCLQSQRDVTVERQRIPIMSPRRDDHEFRIGRLK-------HE 2265
            :....|   :|...:.|.|.:.                      :|..:|....::       ||
  Fly   572 IAATFT---HFLLKNIGGSETF----------------------KDKQDFFYHEVRKFHASYYHE 611

  Fly  2266 R--VKVPRNEDLLMWAMQVMK-----THCNRKSVLEVEFLDEEGTGLGP-TLEFYALVAAEIQRS 2322
            :  :||.| |.:|..:|:.:|     ..|..   .||.|..|:|...|. ..|::.||
  Fly   612 KMALKVQR-EKILESSMKAVKGFSVSDWCGN---FEVTFQGEQGIDWGGLRREWFELV------- 665

  Fly  2323 DLCMWLCDDDLGEDTENSTQSAEGNSKPVGYYV---NRREHGIFPAPL-PQNSEICENVLKYFWF 2383
              |..|.|             |.|     |.:.   ::.:..:.|.|. |.:.:     ||:|.|
  Fly   666 --CSALFD-------------ARG-----GLFCTFHDKHQALVHPNPTRPAHLK-----LKHFEF 705

  Fly  2384 FGVFVAKVLQD-------MRLVDIPLSTSFLQLLCHNKVLSRNLQKVISDRRNGDLSVVSEDSDI 2441
            .|..|.|.|.:       .:||....|.|||..|...:|..:..::              :|.|:
  Fly   706 AGKMVGKCLFESALGGTYRQLVRARFSRSFLAQLIGLRVHYKYFEQ--------------DDPDL 756

  Fly  2442 VETCTK-LLRTDSNKSNAFGGILSLENLKEIDPTRYQFLQEMQNLLLRKQSIEFDDTISAEKKHE 2505
            ..:..| :|.||               |...|.....|::||.:    ..|.:...||
  Fly   757 YLSKIKYILDTD---------------LDATDTLELYFVEEMYD----SSSGQLSKTI------- 795

  Fly  2506 LINELKLQTQNGLEVSLEDLALTFTYLPSSSIYGYTQAELLPNGSSVNVTIDNLEAYCELLMNFI 2570
                                                  ||:|||:...||......|.:.|....
  Fly   796 --------------------------------------ELIPNGAKTRVTNATKNQYLDALAQQR 822

  Fly  2571 LQDGIAQQMKAFSDGFNEVFPLKKLAAFTPSEARMMICGEQFPHWSREDIISYTEPKLGYNKDSP 2635
            |.:.:..::.:|..|.|.:.|...|:.|..:|..:::||      :.|..||..:.....|.:|.
  Fly   823 LCNNVKDEVDSFLKGLNSIIPDNLLSIFDENELELLMCG------TGEYSISDFKAHHIANGNSA 881

  Fly  2636 GFQR----FVNVLLSMSGDERKAFLQFTTGCSSLPPGGLANLHPRLTVVRKVDAGVGSYPSVNTC 2696
            .|:|    |...:.:.|..|....||||||||.|||||...|:|:..:.  .....|:.|:.:||
  Fly   882 EFRRVLAWFWAGVSNFSQTEMARLLQFTTGCSQLPPGGFQELNPQFQIT--AAPTFGNLPTAHTC 944

  Fly  2697 VHYLKLPDYPTEEIMKERLLTATKE--KGF 2724
            .:.|.||||.:.|..::.||.|..|  :||
  Fly   945 FNQLCLPDYESYEQFEKSLLLAISEGSEGF 974

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ufd4	NP_609369.1	ANK repeat	393..420	CDD:293786
		ANK	396..509	CDD:238125
		ANK repeat	422..453	CDD:293786
		ANK repeat	455..484	CDD:293786
		F5_F8_type_C	1173..1298	CDD:329041
		MIB_HERC2	1333..1389	CDD:310955
		DamX	1576..>1725	CDD:330571
		HECTc	2265..2725	CDD:238033	117/486 (24%)
CG4238	NP_001259896.1	IG_FLMN	238..336	CDD:214720	20/117 (17%)
		Filamin	238..336	CDD:279024	20/117 (17%)
		HECTc	615..975	CDD:238033	116/482 (24%)
		HECTc	642..974	CDD:214523	106/449 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446951
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830