Protein Alignment Utx and ECM5

DIOPT Version :9

• Sequence 1: NP_609368.3
• Gene: Utx / 34377
• FlyBaseID: FBgn0260749
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: NP_013901.1
• Gene: ECM5 / 855214
• SGDID: S000004788
• Length: 1411
• Species: Saccharomyces cerevisiae
• Alignment Length: 1095
• Identity: 203/1095 - (18%)
• Similarity: 343/1095 - (31%)
• Gaps: 385/1095 - (35%)

  Fly    13 RELDSRYYGFLDLSNSKNAELRNLVQQTITNLQNYIANGQVHESKNSSDNKNAIQKFEPSTQAGE 77
            |||.  |.|  .:.:|.:..||:...:.:.:...|....|.  ::|:..|::.::        .|
Yeast   247 RELG--YSG--RIMSSLSTSLRSAYAKILLDFDIYEEEEQA--ARNNEKNEDMVE--------SE 297

  Fly    78 HMENTSSRNNDDTKPFEQDAKEKVSIIE--------EKHQD-EH------YVNALC--KLGHLH- 124
            ...:::||:.|:.:|..:.||....:..        ::.:| :|      |.|:|.  |||:..
Yeast   298 IFRHSNSRSRDEEEPLHKKAKIHRDVFRAGSINHEFKRMRDIKHIKGFPTYFNSLTEFKLGYTQS 362

  Fly   125 ---LLLGE----YSEALSAYQKYLRFRENNYWTNHAFIYGIGVAYFKLRCFKWAI-----KSFQE 177
               .|.|.    :...:..|.|      :.|.|..:.:|.:...|.|......||     .|:.:
Yeast   363 TETTLPGYDFTFWENGMEIYDK------SKYETKTSPVYNLRQYYEKSLAVFTAIVAKFGSSYPD 421

  Fly   178 LLYLSPNFTCANEVHLRLGLMLKHCGEFHIALKHLQLALLYTYPSTFSELQVKFQIAHLYEVQNK 242
            |..............|...|:.:|..:|.|. ..|.|......|...|..: ||.|.::.:..|.
Yeast   422 LFAKHTTLPQKEFERLYFHLLSEHFIDFEID-TGLGLPCSMRSPGNNSSNE-KFAIKNILDQWNL 484

  Fly   243 HKAAKDGYEFLLNEKNISLELKADVYR------QLGWMYHC-----------------------V 278
            ....       |||.::...|..|:..      .:|.::.|                       |
Yeast   485 DNIP-------LNELSLLQHLDLDMANFTRTTYDIGMLFSCQGWSVSDHFLPSIDFNHLGSTKLV 542

  Fly   279 ECLGEKKEREANALNFLQKS----IEADPKSGQS-----LYLLGRCY------------------ 316
            ..:..|...:..||....||    |::.|:...|     .::....|
Yeast   543 YSIAPKDMEKFEALIARGKSEWDTIQSRPRYSTSDDELKSFIETDFYKSFLDAEQSADYSNTGDN 607

  Fly   317 ----------AGINKVHDA-----------FLA-----YRNSVEKSE-----GNADTWCSIGV-L 349
                      || |.:||.           .||     |:.:.|:..     ..|.| ||||. .
Yeast   608 SKNSFPEDKIAG-NTLHDGSQSDFIFEPNFILANGIKLYKTTQEQGSYIFKFPKAFT-CSIGSGF 670

  Fly   350 YQQQN---QPTDALQAYICAVQLDKDHKAAWT----------------------NLGILYESCGQ 389
            |..||   .|:..|:.        ....|.||                      |..:|.:.|
Yeast   671 YLSQNAKFAPSSWLRF--------SSEAAKWTSKMGFLPGLDVNQLLINALLNSNNPVLRKKC-- 725

  Fly   390 LRDAYACYLNATKQISFQKSSLIRKKQAIRMKKDTI--------GLSK-----GLSQR------- 434
             ||..:.|:....:.|.:...||.....:..|.:.|        ||||     |..||
Yeast   726 -RDLISNYVVEEAENSKKLGELIGTVDVVYNKLNYISDISLESTGLSKIVVTHGALQRNLSLKEF 789

  Fly   435 ITFLEGQLSQAPLPSITSKRRQLCSI---EEAWNLPISLEMNSRQQQTAQMLPRQVTKQSPVQGP 496
            :..||...:.|         ..:|.|   :::.||.:.|............|       ..:..|
Yeast   790 VVLLEKPENGA---------HSICGIPIRDQSGNLNVCLHSYFDSASLGIAL-------DGLDKP 838

  Fly   497 PPPY--PHSQLSQSPIPSKRIKEDGTSQQEVTQNN---SQTSAQNLIN--ISESLNQRNFNAMPE 554
            |..|  .|:             ||...:.:|...:   ::|...|:|.  ||.:.:...||.|..
Yeast   839 PTSYLLVHN-------------EDFEKKWDVLMTSTFRNRTVPLNIIQYLISHTDSNTEFNRMLR 890

  Fly   555 SNKSSE-------QSVLDTFDDISNDI-----------------YKQNESIKLERLSQD----AL 591
            ||....       :..:.||.|:|..:                 :..|.:..||.|.:.    ::
Yeast   891 SNFDDSLLLIEKCKKFIKTFVDVSCSVKDVDFGNGFNLRHLPLKFSDNMADNLESLYESVRKCSI 955

  Fly   592 SNNE----------------DSRHDFIGGDNADISTTFKIQMDSKQLMVAVKLLPIDEPPVHCTI 640
            ..:|                |:| |.|.|:|.|:..    ::..|.|.:.:|:       .:.|.
Yeast   956 EFSEKPTIIRLYHVSRQFPIDNR-DIIDGNNLDLLK----ELYQKSLTIPLKV-------SYWTK 1008

  Fly   641 LQVNAPPPSPPDCPPQKLTRDQLLPPTPSVHLEN--------KKHAFSPQLQ---EFCLKH---- 690
            |             .:|:.|.:.|.....:.:|.        .|::. |.|.   ||.||:
Yeast  1009 L-------------TRKICRLEWLSVYEHIFIERCDIKNEDPAKYSL-PLLYSYFEFGLKYCDSE 1059

  Fly   691 ---PIAVVRGLAGVLKLDLGLFSTKTLVEANPDHSVEVRTQVHQSPDENWDTSQGKRVWACISHR 752
               .:..||.|  :||..              |...:||..:.:.|......|..:.|.
Yeast  1060 DIDKLGEVRKL--ILKYQ--------------DMMQKVRVFLKKDPPSKISLSDLEDVL------ 1102

  Fly   753 SHTTIAKYAQYQASSFQDSLKLILPQDESDKGFPGSQAMSDSDSKDSVSNSNIVLKRKKHKINSK 817
              ..|.:|.....|||...|..::.:.|:.|.......:.::|:.|.:..    |.||.   :.|
Yeast  1103 --LDIEEYRLPIQSSFFSELDYVIREIENAKKMNDVNILYNTDNIDKIDE----LIRKN---DPK 1158

  Fly   818 MLRF-----GTNVD----LSDE-------------KKWKPQLTELQKLPAFARVI 850
            .::|     |:.:|    .||.             |.|...|.::.:...|..::
Yeast  1159 FVKFANQFNGSRLDKRPLASDNSGSVKAKQELKVFKLWNQHLDQIMQKNKFIEIL 1213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Utx	NP_609368.3	TPR repeat	147..181	CDD:276809	9/38 (24%)
		TPR_11	156..216	CDD:290150	14/64 (22%)
		TPR repeat	186..216	CDD:276809	7/29 (24%)
		TPR repeat	228..255	CDD:276809	4/26 (15%)
		TPR_11	264..337	CDD:290150	22/154 (14%)
		TPR repeat	265..300	CDD:276809	9/67 (13%)
		TPR repeat	307..334	CDD:276809	10/75 (13%)
		TPR_11	339..402	CDD:290150	20/88 (23%)
		TPR repeat	339..369	CDD:276809	11/33 (33%)
		TPR_1	340..373	CDD:278916	11/36 (31%)
		TPR repeat	374..402	CDD:276809	9/49 (18%)
		JmjC	870..978	CDD:202224
ECM5	NP_013901.1	BRIGHT	187..280	CDD:128777	9/36 (25%)
		cupin_RmlC-like	512..662	CDD:424065	21/150 (14%)
		PHD_Ecm5p_Lid2p_like	1240..1287	CDD:276993

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0055
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900