Protein Alignment Utx and SWA2

DIOPT Version :9

• Sequence 1: NP_609368.3
• Gene: Utx / 34377
• FlyBaseID: FBgn0260749
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: NP_010606.1
• Gene: SWA2 / 851918
• SGDID: S000002728
• Length: 668
• Species: Saccharomyces cerevisiae
• Alignment Length: 516
• Identity: 105/516 - (20%)
• Similarity: 187/516 - (36%)
• Gaps: 138/516 - (26%)

  Fly   379 NLGILYESCGQLRD---AYACYLNATKQISFQKSSL-IRKKQA-IRMKKDTIGLSKGLSQRI-TF 437
            :||:..|...:..:   .|..||...|....:::.| ||||:: |:|:|      .|||..: |.
Yeast   152 SLGLSIEEATEFYENDVTYERYLEILKSKQKERNDLAIRKKESGIKMEK------SGLSNIVGTD 210

  Fly   438 LEGQLSQAPLPSITSKRRQLCSIEEAWNLPISLEMNSRQQQTAQMLPRQVTKQSPVQGPPPPYPH 502
            .....|.|  ....:|.::|  :::..:.|  .|.|.|           :...|........|..
Yeast   211 SNNLFSMA--TDFFNKGKKL--VDQWTSFP--PEANDR-----------LNNYSKTHDKVEDYDL 258

  Fly   503 SQLSQSPIPSKRIKEDGTSQQEVTQN--NSQTSAQNLINISESLNQRNFNAMPESNKSSEQSVLD 565
            .|::.|  |::.:.||    .||.:|  .:....|:|:...|:.........|:.:.||..
Yeast   259 PQVNDS--PNRILFED----NEVVENLPPADNPDQDLLTDFETKIDITKRTAPDVSHSSSP---- 313

  Fly   566 TFDDISNDIYKQNESIKLERLSQDAL-----------SNNEDSRHDFIGGDNADISTTFKIQMDS 619
                 ::.|..:..|.:.|.|.:|:|           .:||||.   :..:|::..:|..|.
Yeast   314 -----TSGILIEENSRRNEPLIEDSLLDFSEGNLTNSKSNEDST---LFNENSNTDSTIPIS--- 367

  Fly   620 KQLMVAVKLLPIDEPPVHCTILQVNAPPPSPPDCPPQKLTRDQLLPPTPSVHLENKKHAFSPQLQ 684
                 .::|...:|.....|.|..|.               |.:          |....:...|.
Yeast   368 -----DIELSGYNEFKAKGTSLFKNG---------------DYI----------NSLQEYEKSLN 402

  Fly   685 EFCLKHPIAVVRGLAGVL--KLDLGLFS-----TKTLVEANPDHSVEVRTQVHQS-PDENWDTSQ 741
            ...|.||:.:: .|:.::  :|.:|.:|     :...:|..|....:.:.::..| |:.:::.
Yeast   403 TLPLNHPLRII-ALSNIIASQLKIGEYSKSIENSSMALELFPSSKAKWKNKISNSDPERSFND-- 464

  Fly   742 GKRVWACISHRSHTTIAKYAQYQASSFQ--DSLK--------LILPQDESDKGFPGSQAMSDSDS 796
               :|..|..|           :|.||:  :|.|        ||......||...|.:...|..:
Yeast   465 ---IWPKIMIR-----------RAESFEHLESFKKALETYQELIKKNFFDDKIMQGKRRCQDFIN 515

  Fly   797 KDSVSNSNIVLKR--------KKHKINSKMLRFGTNVDLSDEKKWKPQLTELQKLPAFARV 849
            ...|..|..|.|:        ||..:.:.......:||.:.|.| |.:| |..||..:.:|
Yeast   516 PPPVKKSMPVKKKTTTTSPATKKQNLTASSSNSPISVDSTSEIK-KREL-ENAKLALYDKV 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Utx	NP_609368.3	TPR repeat	147..181	CDD:276809
		TPR_11	156..216	CDD:290150
		TPR repeat	186..216	CDD:276809
		TPR repeat	228..255	CDD:276809
		TPR_11	264..337	CDD:290150
		TPR repeat	265..300	CDD:276809
		TPR repeat	307..334	CDD:276809
		TPR_11	339..402	CDD:290150	6/25 (24%)
		TPR repeat	339..369	CDD:276809
		TPR_1	340..373	CDD:278916
		TPR repeat	374..402	CDD:276809	6/25 (24%)
		JmjC	870..978	CDD:202224
SWA2	NP_010606.1	Ubiq-assoc	138..181	CDD:401184	7/28 (25%)
		TPR	<374..497	CDD:223533	28/164 (17%)
		TPR repeat	374..402	CDD:276809	6/52 (12%)
		TPR repeat	407..441	CDD:276809	6/34 (18%)
		TPR repeat	467..495	CDD:276809	8/38 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900