DRSC/TRiP Functional Genomics Resources

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Protein Alignment Utx and Tmtc4

DIOPT Version :9

Sequence 1:NP_609368.3 Gene:Utx / 34377 FlyBaseID:FBgn0260749 Length:1136 Species:Drosophila melanogaster
Sequence 2:NP_001347527.1 Gene:Tmtc4 / 70551 MGIID:1921050 Length:741 Species:Mus musculus


Alignment Length:341 Identity:70/341 - (20%)
Similarity:121/341 - (35%) Gaps:88/341 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   153 AFIYGIGVAYFKLRCF----KWAIKSFQELLYLSPNFTCA--NEVHLRLGLMLKHCGEFHIALKH 211
            |.|.|| :....|||.    :|   ..:|.|:.|....|.  .:||..:|..|...|....|:|:
Mouse   444 AIILGI-LLINALRCVIRSGEW---RSEEQLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKY 504

  Fly   212 LQLALLYTYPSTFSELQVKFQIAHLYEVQNKHKAAKDGYEFLLNEKNISLELKADVYRQLGWMYH 276
            .:.|:                     .:..|:..|.:....:|.|:|                  
Mouse   505 YREAV---------------------RLNPKYVHAMNNLGNILKERN------------------ 530

  Fly   277 CVECLGEKKEREANALNFLQKSIEADPKSGQSLYLLGRCYAGINKVHDAFLAYRNSVEKSEGNAD 341
                  |.:|.|    ..|..:::..|....:...||.....:.:..:|..:||.:::......|
Mouse   531 ------ELQEAE----ELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPD 585

  Fly   342 TWCSIGVLYQQQNQPTDALQAYICAVQLDKDHKAAWTNLGILYESCGQLRDAYACYLNATK---- 402
            .:.::|.||...|:..|||.|:..|..|..:|..||.|:.||.::.|.|..|.|....|.:    
Mouse   586 CYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALQLIPN 650

  Fly   403 --QISFQKSSLIRKKQAIRMKKDTIGLSKGLSQRITFLEGQLSQAPLPSITSKRRQLCSIEEAW- 464
              .:.|..::::.|.|            |.......||:...:.   |::.|....|..:...| 
Mouse   651 DHSLMFSLANVLGKSQ------------KYKESEALFLKAIKAN---PNVASYHGNLAVLYHRWG 700

  Fly   465 -------NLPISLEMN 473
                   :..|||:::
Mouse   701 HLDSAKKHYEISLQLD 716

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
UtxNP_609368.3 TPR repeat 147..181 CDD:276809 10/31 (32%)
TPR_11 156..216 CDD:290150 17/65 (26%)
TPR repeat 186..216 CDD:276809 8/31 (26%)
TPR repeat 228..255 CDD:276809 2/26 (8%)
TPR_11 264..337 CDD:290150 10/72 (14%)
TPR repeat 265..300 CDD:276809 4/34 (12%)
TPR repeat 307..334 CDD:276809 5/26 (19%)
TPR_11 339..402 CDD:290150 22/62 (35%)
TPR repeat 339..369 CDD:276809 10/29 (34%)
TPR_1 340..373 CDD:278916 11/32 (34%)
TPR repeat 374..402 CDD:276809 10/27 (37%)
JmjC 870..978 CDD:202224
Tmtc4NP_001347527.1 DUF1736 292..366 CDD:369859
TPR 1 448..481 10/36 (28%)
TPR 481..717 CDD:223533 58/300 (19%)
TPR 2 482..515 8/53 (15%)
TPR repeat 482..510 CDD:276809 8/48 (17%)
TPR repeat 515..545 CDD:276809 8/57 (14%)
TPR 3 517..549 9/59 (15%)
TPR 4 550..583 5/32 (16%)
TPR repeat 550..578 CDD:276809 5/27 (19%)
TPR 5 584..617 11/32 (34%)
TPR repeat 584..610 CDD:276809 9/25 (36%)
TPR repeat 618..646 CDD:276809 10/27 (37%)
TPR 6 619..651 10/31 (32%)
TPR repeat 651..681 CDD:276809 6/41 (15%)
TPR 7 652..685 7/47 (15%)
TPR 8 686..719 6/31 (19%)
TPR repeat 686..714 CDD:276809 5/27 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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