DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Utx and Fkbpl

DIOPT Version :9

Sequence 1:NP_609368.3 Gene:Utx / 34377 FlyBaseID:FBgn0260749 Length:1136 Species:Drosophila melanogaster
Sequence 2:NP_063926.1 Gene:Fkbpl / 56299 MGIID:1932127 Length:347 Species:Mus musculus


Alignment Length:412 Identity:76/412 - (18%)
Similarity:129/412 - (31%) Gaps:162/412 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly   505 LSQSPIPSKRIKEDGTSQQEVTQNNSQTSAQNLINISESLNQRNFNAMPESNKSSEQSVLDTFDD 569
            :..|||  ..:.|..|:|.:..:.|    ||.::|.:....||:...:||:.|      :....|
Mouse     1 METSPI--SPMNEKNTAQPQQREEN----AQQILNTAIPFRQRSPGLLPEALK------VGVRPD 53

  Fly   570 ISNDIYKQNESIKLERLSQDALSNNEDSRHDFIGGDNADISTTFKIQMDSKQLMVAVKLLPIDEP 634
            .:|.|.:                 .::..|...|           .:.||.|..|:.     :|.
Mouse    54 PANQIVE-----------------TQEIEHPVAG-----------FEGDSDQFQVST-----NEM 85

  Fly   635 PVHCTILQVNAPPPSPPD---CPPQKLTRDQLLPPTPSVHLENKKHAF-SPQLQEFCLKHPIAVV 695
            ..|   ||.:       |   ||.....:..::|          .|.. .|:|...|        
Mouse    86 AEH---LQAS-------DLWYCPDGSFVKKIIVP----------GHGLDKPKLGSKC-------- 122

  Fly   696 RGLAGVLKLDLGLFSTKTLVEANPDHSVEVRTQVHQSPDENWDTSQGKRVWACISHRSHTTIAKY 760
                .||.|.....|      ..|:...|:...:.|..::.|    |:.:..|:           
Mouse   123 ----QVLALGFPFGS------GMPEGWTELTIGIGQWREKMW----GELMEKCL----------- 162

  Fly   761 AQYQASSFQDSLKLILPQDESDK-GFPGSQA----------MSDSDSKDSVSNSNIVLKRKKHKI 814
                     :|::    |.|..| ..|||.|          .:..||.:..:.....|.:::|:.
Mouse   163 ---------ESMR----QGEEAKIHLPGSSAPLAKLRLDSFTNGRDSWEMEAMEKEALAKEEHRR 214

  Fly   815 NSKMLRFGTNVDLSDEKKWKPQ---------LTELQKLP---------AFARVISAANMLSHVGH 861
            .:::.|.|           .||         |..|..||         .:|. ::|..:|  :||
Mouse   215 GTELFRAG-----------NPQGAARCYGRALRLLLTLPPPGPPERTTLYAN-LAACQLL--LGH 265

  Fly   862 VILGMNTVQLYMKVPGSRTPGH 883
            ..|...:....::    |.|||
Mouse   266 PQLAAQSCDRVLE----REPGH 283

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
UtxNP_609368.3 TPR repeat 147..181 CDD:276809
TPR_11 156..216 CDD:290150
TPR repeat 186..216 CDD:276809
TPR repeat 228..255 CDD:276809
TPR_11 264..337 CDD:290150
TPR repeat 265..300 CDD:276809
TPR repeat 307..334 CDD:276809
TPR_11 339..402 CDD:290150
TPR repeat 339..369 CDD:276809
TPR_1 340..373 CDD:278916
TPR repeat 374..402 CDD:276809
JmjC 870..978 CDD:202224 4/14 (29%)
FkbplNP_063926.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..24 7/28 (25%)
TPR_11 208..281 CDD:290150 16/90 (18%)
TPR 1 208..241 7/43 (16%)
TPR repeat 208..236 CDD:276809 5/38 (13%)
TPR repeat 249..279 CDD:276809 6/36 (17%)
TPR 2 250..283 8/39 (21%)
TPR_11 252..315 CDD:290150 10/39 (26%)
TPR 3 284..317 76/412 (18%)
TPR repeat 284..312 CDD:276809 76/412 (18%)
TPR_1 285..317 CDD:278916
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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