DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Utx and ATPsynbeta

DIOPT Version :9

Sequence 1:	NP_609368.3	Gene:	Utx / 34377	FlyBaseID:	FBgn0260749	Length:	1136	Species:	Drosophila melanogaster
Sequence 2:	NP_001259081.1	Gene:	ATPsynbeta / 43829	FlyBaseID:	FBgn0010217	Length:	511	Species:	Drosophila melanogaster

Alignment Length:	460	Identity:	82/460 - (17%)
Similarity:	144/460 - (31%)	Gaps:	157/460 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   246 AKDGYEFLLNEKN-------ISLELKADVYRQLGWMYHCVECLGEK-KER-----------EANA 291
            |.||.|.|:..:.       |.:.:.|:...::      :..:||. .||           .|.|
  Fly    95 AMDGTEGLVRGQKVLDTGYPIRIPVGAETLGRI------INVIGEPIDERGPIDTDKTAAIHAEA 153

  Fly   292 LNFLQKSIE--------------ADPKSGQSLYLLGRCYAG-----------INKVHDAFLAYRN 331
            ..|:|.|:|              |....|..:.|.|....|           :.|.|..:..:..
  Fly   154 PEFVQMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAG 218

  Fly   332 SVEKS-EGN--------------ADTWCSIGVLYQQQNQPTDALQAYICAVQLDKDHKAAWTNLG 381
            ..|:: |||              .|....:.::|.|.|:|..|..            :.|.|.|.
  Fly   219 VGERTREGNDLYNEMIEGGVISLKDKTSKVALVYGQMNEPPGARA------------RVALTGLT 271

  Fly   382 IL-YESCGQLRDAYACYLNATK--QISFQKSSLIRKKQAIRMKKDTIGLSKG-LSQRITFLEGQL 442
            :. |....:.:|......|..:  |...:.|:|:.:..:....:.|:....| :.:|||
  Fly   272 VAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGSMQERIT------ 330

  Fly   443 SQAPLPSITSKRRQLCSIEEAWNLPISLEMNSRQQQTAQMLPRQVTKQSPVQGPPPPYPHSQLSQ 507
                    |:|:..:.|::..:                       .....:..|.|....:.|..
  Fly   331 --------TTKKGSITSVQAIY-----------------------VPADDLTDPAPATTFAHLDA 364

  Fly   508 SPIPSKRIKEDGT-SQQEVTQNNSQTSAQNLINISESLNQRNFNAMPESNKSSEQSVLDTFDDIS 571
            :.:.|:.|.|.|. ...:...:.|:....|:|      .|.::|.     ....|.:|..
  Fly   365 TTVLSRAIAELGIYPAVDPLDSTSRIMDPNII------GQEHYNV-----ARGVQKILQD----- 413

  Fly   572 NDIYKQNESIKLERLSQDALSNNEDSRHDFIGGDNADISTTFKIQ-MDSKQLMVAV-------KL 628
               ||..:.| :..|..|.||..          |...::...||| ..|:...||.       ||
  Fly   414 ---YKSLQDI-IAILGMDELSEE----------DKLTVARARKIQRFLSQPFQVAEVFTGHAGKL 464

  Fly   629 LPIDE 633
            :|:::
  Fly   465 VPLEQ 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Utx	NP_609368.3	TPR repeat	147..181	CDD:276809
		TPR_11	156..216	CDD:290150
		TPR repeat	186..216	CDD:276809
		TPR repeat	228..255	CDD:276809	5/8 (63%)
		TPR_11	264..337	CDD:290150	19/110 (17%)
		TPR repeat	265..300	CDD:276809	10/46 (22%)
		TPR repeat	307..334	CDD:276809	5/37 (14%)
		TPR_11	339..402	CDD:290150	13/77 (17%)
		TPR repeat	339..369	CDD:276809	7/43 (16%)
		TPR_1	340..373	CDD:278916	6/32 (19%)
		TPR repeat	374..402	CDD:276809	6/28 (21%)
		JmjC	870..978	CDD:202224
ATPsynbeta	NP_001259081.1	PRK09280	44..507	CDD:236447	82/460 (18%)
		ATP-synt_ab_N	46..112	CDD:280947	5/16 (31%)
		F1-ATPase_beta	114..393	CDD:238553	54/333 (16%)
		ATP-synt_ab_C	401..508	CDD:278722	20/93 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0055
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900