back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Utx and odad4

DIOPT Version :9

Sequence 1:	NP_609368.3	Gene:	Utx / 34377	FlyBaseID:	FBgn0260749	Length:	1136	Species:	Drosophila melanogaster
Sequence 2:	NP_956610.1	Gene:	odad4 / 393286	ZFINID:	ZDB-GENE-040426-995	Length:	486	Species:	Danio rerio

Alignment Length:	495	Identity:	98/495 - (19%)
Similarity:	172/495 - (34%)	Gaps:	149/495 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LTFEDD---CLIRELDSRYYGFLDLSNSKNA---------------------------------- 31
            ||.:.|   ||:    ||...::.|.:::||
Zfish    41 LTLQPDNKNCLV----SRSRCYVKLGDAENALKDAESSLKDNKNYFKGLYQKAEALYTMGDFEFA 101

  Fly    32 --------ELRNLVQQTITNLQNYIANGQVHESKNSSDNKNAIQKFEPS-TQAGEHMENTSSRNN 87
                    :||..:|:....:|.  |...:..|..|..:...:.|.:.| ...|.|.:|.:..|.
Zfish   102 LVYYHRGHKLRPELQEFRLGIQK--AQEAIDNSVGSPSSVKLVNKGDLSFFHNGVHPQNLNPSNK 164

  Fly    88 DDTKPFEQ--DAKEKVS--IIEEKHQDEHYVNAL--------CKLGH----LHLLLGEYSEALSA 136
            .::|...:  |..||.:  ::.|.:.|..|:..|        ||:..    ..|::|..|
Zfish   165 KESKKHSKKTDKGEKTAKQLLGELYSDREYLKKLLQDEDLVKCKIRSGERVQDLIVGSIS----- 224

  Fly   137 YQKYLRFRENNYWTNHAFIYGIGVAYFKLRCFKWAIKSFQELLYLSPNFTCANEVHLRLGLMLKH 201
               ||..| ..:|.....||.      :.|..|...:.:.::|:..|    ::.....|.
Zfish   225 ---YLDTR-MAFWQQQKPIYA------RQRDRKLMQQQWSKVLHKPP----SDPTRYVLS----- 270

  Fly   202 CGEFHIALKHLQLALLYTYPSTFSELQVKFQIAHLYEVQNKHKAAKDGYEFLLNEKNISLELKAD 266
                  :|:.:..||...|..           :.|.:.:...|..||..|..|..||   |:..:
Zfish   271 ------SLEEIDTALSAGYTE-----------SGLNKARELMKVVKDWSEDALPNKN---EVLGN 315

  Fly   267 VYRQLGWMYHCVECLGEKKEREANALNFLQKSIE-------ADPKSGQSLYLLGRCYAGINKVHD 324
            ::..:|   :.:..||...    .||:..:|.:|       .|.|| ::|..:||.||.|.|...
Zfish   316 LHSYIG---NALMDLGNMD----RALHHHEKDLELAKKCDLTDSKS-RALDNIGRVYARIGKFQQ 372

  Fly   325 AFLAYRNSVEKSEGNAD-TWC--SIGVLYQQQNQPTDALQAY----ICAVQLDKDHKAAWTNLGI 382
            |...:...:..:.|..: .|.  .||..|.:..:..:| :.|    :.|.....|.|  |
Zfish   373 AIEVWEKKLPLACGGLEKAWLFHEIGRCYLELKRYMEA-RDYGSRSLMAADDISDEK--W----- 429

  Fly   383 LYESCGQLRDAYACYLNATKQISFQKSSLIRKKQAIRMKK 422
                  || :|......|..::|..|:|::..::|:...|
Zfish   430 ------QL-NASVLMAQAELKLSNYKASVLHFERALERAK 462

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.