DRSC/TRiP Functional Genomics Resources

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Protein Alignment Utx and Tmtc1

DIOPT Version :9

Sequence 1:NP_609368.3 Gene:Utx / 34377 FlyBaseID:FBgn0260749 Length:1136 Species:Drosophila melanogaster
Sequence 2:NP_945318.2 Gene:Tmtc1 / 387314 MGIID:3039590 Length:942 Species:Mus musculus


Alignment Length:471 Identity:98/471 - (20%)
Similarity:162/471 - (34%) Gaps:150/471 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    42 TNLQNYIANGQVHES-----KNSSDNKNAIQKFEPSTQAGEHMENTSSRNNDDTKPFEQ-DAK-- 98
            :.:|....|.:||.:     |:...||.||..:..:.:.  :..:.|:.||..|...:. :||  
Mouse   534 SGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKL--YPRHASALNNLGTLTKDMAEAKMY 596

  Fly    99 -EKVSIIEEKHQDEHYVNALCKLGHL----------HLLLGE-----------YSEALSAYQKYL 141
             :|...:..:|.     .||..||:|          .:||.|           ||...|...:..
Mouse   597 YQKALQLHPQHN-----RALFNLGNLLKSQEKTEEAIMLLKESIKYGPDFADAYSSLASLLAEQE 656

  Fly   142 RFRE-------------------NNYWTNHAFIYGIGVAYFKLRCFKWAIKSFQELLYLSPNFTC 187
            ||:|                   |||   ..|:...|..       :.|:..:|:.:.|||:...
Mouse   657 RFKEAEDIYQAGIKNCPDSSDLHNNY---AVFLVDSGFP-------EKAVAHYQQAIQLSPSHHV 711

  Fly   188 ANEVHLRLGLMLKHCGE-------FHIALKHLQLALLYTYPSTFSELQVKFQIAHLYEVQNKHKA 245
            |   .:.||.:.:..||       :..|||..:.|            :|...:..||....:||.
Mouse   712 A---VVNLGRLYRSLGENSKAEEWYRRALKVARTA------------EVLSPLGALYYNTGRHKE 761

  Fly   246 AKDGYEFLLNEKNISLELKADVYRQLGWM-----------------YHCVEC------LGEKKER 287
            |.:.|...::.:....||:..:.:.|..|                 ..|:||      :..|:|.
Mouse   762 ALEVYREAVSLQPSQRELRLALAQVLAVMGQTKEAEKITSHIVSEEPRCLECYRLLSAIHSKQEH 826

  Fly   288 EANALNFLQKSIEADPKSGQSLYLLGRCYAGINKVHDAFLAYRNSVEKSEGNADTWCSIGVLYQQ 352
            ...||..::|:::..||..:             .:.:.|....|.:                 ::
Mouse   827 HGKALEAIEKALQLKPKDPK-------------VISELFFTKGNQL-----------------RE 861

  Fly   353 QNQPTDALQAYICAVQLDKDHKAAWTNLGILYESCGQLRDAYACYLNATKQISFQK--------- 408
            ||....|.::|..||.||.|...||.|:|.:....|....|.|.|..|.|.:...|         
Mouse   862 QNLLDKAFESYEAAVTLDPDQAQAWMNMGGIRHIQGSYVSARAYYERALKLVPDSKLLKENLAKL 926

  Fly   409 SSLIRKKQAIRMKKDT 424
            ..|.|:.|.:|.:..|
Mouse   927 DRLERRLQEVRERDQT 942

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
UtxNP_609368.3 TPR repeat 147..181 CDD:276809 6/33 (18%)
TPR_11 156..216 CDD:290150 14/66 (21%)
TPR repeat 186..216 CDD:276809 8/36 (22%)
TPR repeat 228..255 CDD:276809 7/26 (27%)
TPR_11 264..337 CDD:290150 14/95 (15%)
TPR repeat 265..300 CDD:276809 10/57 (18%)
TPR repeat 307..334 CDD:276809 2/26 (8%)
TPR_11 339..402 CDD:290150 18/62 (29%)
TPR repeat 339..369 CDD:276809 6/29 (21%)
TPR_1 340..373 CDD:278916 8/32 (25%)
TPR repeat 374..402 CDD:276809 9/27 (33%)
JmjC 870..978 CDD:202224
Tmtc1NP_945318.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 245..285
DUF1736 351..425 CDD:285594
TPR_11 542..605 CDD:290150 15/64 (23%)
TPR 1 543..576 7/34 (21%)
TPR_2 543..576 CDD:285020 7/34 (21%)
TPR repeat 543..571 CDD:276809 7/27 (26%)
TPR repeat 576..603 CDD:276809 7/26 (27%)
TPR 2 577..607 7/29 (24%)
TPR 577..607 CDD:197478 7/29 (24%)
TPR_17 596..628 CDD:290167 7/36 (19%)
TPR 3 608..641 8/37 (22%)
TPR repeat 608..636 CDD:276809 8/32 (25%)
TPR 621..940 CDD:223533 75/373 (20%)
TPR 4 642..675 6/32 (19%)
TPR repeat 642..670 CDD:276809 6/27 (22%)
TPR repeat 675..705 CDD:276809 7/39 (18%)
TPR 5 676..709 10/42 (24%)
TPR 6 710..742 8/34 (24%)
TPR repeat 710..738 CDD:276809 6/30 (20%)
TPR_7 715..744 CDD:289919 8/40 (20%)
TPR 7 743..776 8/44 (18%)
TPR repeat 743..771 CDD:276809 8/39 (21%)
TPR_14 749..786 CDD:290164 8/36 (22%)
TPR repeat 776..806 CDD:276809 4/29 (14%)
TPR 8 811..844 8/32 (25%)
TPR repeat 812..839 CDD:276809 7/26 (27%)
TPR repeat 844..878 CDD:276809 8/63 (13%)
TPR 9 849..882 10/49 (20%)
TPR 10 883..916 10/32 (31%)
TPR_1 883..915 CDD:278916 10/31 (32%)
TPR repeat 883..911 CDD:276809 9/27 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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