DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Utx and CG31690

DIOPT Version :9

Sequence 1:NP_609368.3 Gene:Utx / 34377 FlyBaseID:FBgn0260749 Length:1136 Species:Drosophila melanogaster
Sequence 2:NP_995615.2 Gene:CG31690 / 33455 FlyBaseID:FBgn0051690 Length:859 Species:Drosophila melanogaster


Alignment Length:380 Identity:78/380 - (20%)
Similarity:133/380 - (35%) Gaps:112/380 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    85 RNNDDTKPFEQDAKEKVSIIEEKHQDEHYVNALCKLGHLHLLLGEYSEALSAYQKYLRFRENNYW 149
            |.|.|.:..||..:..:||...|        ||..||.:....|.|.||    :..||....:..
  Fly   497 RRNLDWRDEEQLFRSAISINPPK--------ALGNLGSVLSAQGRYEEA----ELTLRMTLGHRP 549

  Fly   150 TNHAFIYGIGVAYFKLRCFKWAIKSFQELLYLSPNFTCANEVHLRLGLMLKHCGEF--------- 205
            |.....:.:||.:.|...|..||..|:..:.|.|....|   :|.||..|...|:.         
  Fly   550 TMADAHFNLGVVHQKQLNFSSAIPCFRRAIELRPQLAVA---YLNLGTSLISLGDHRQEAISVLR 611

  Fly   206 ---------------HIALK---HLQLALLYTYPSTFSEL---------------QVKFQIAH-- 235
                           |:..:   :|||::||.......:.               |.:..:.|  
  Fly   612 TGARLEGSGVRDRGAHVEARYTCYLQLSVLYRSDGRLQDAAAALRESLKALPLLPQKQRAVLHLR 676

  Fly   236 ----LYEVQNKHKAAKDGYEFLLNEKNISLELKAD------VYRQL------------GWM---- 274
                |.|:|:.::|.        :::.::::|:.:      .|.|.            .|.    
  Fly   677 LGEILAELQDWNEAE--------HQQRLAMQLQPEQGAAYVTYGQTLARNGSRLAEAESWFKRAL 733

  Fly   275 ----------YHCVECLGEKKEREANALNFLQKSIEADPKSGQSLYLLGRCYAG----INKVHDA 325
                      :|..:.| |::||...||....::....|:.    |.|..|.|.    :|::.:|
  Fly   734 QLAPLEPSSHHHYADFL-EQQERHHEALGLRLRAAALAPQD----YTLQSCVADALRLLNRLAEA 793

  Fly   326 FLAYRNSVEKSEGNADTWCSIGVLYQQQNQPTDALQAYICAVQLDKDHKAAWTNL 380
            .|.||.:|......|....::|.:.|.:....:|:..|..|::|...|..:..||
  Fly   794 ELWYRKAVTLQPMAAHAHANLGAILQMRGLRKEAVACYHKALELQPGHAISRANL 848

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
UtxNP_609368.3 TPR repeat 147..181 CDD:276809 8/33 (24%)
TPR_11 156..216 CDD:290150 19/86 (22%)
TPR repeat 186..216 CDD:276809 10/56 (18%)
TPR repeat 228..255 CDD:276809 6/32 (19%)
TPR_11 264..337 CDD:290150 21/108 (19%)
TPR repeat 265..300 CDD:276809 10/66 (15%)
TPR repeat 307..334 CDD:276809 9/30 (30%)
TPR_11 339..402 CDD:290150 10/42 (24%)
TPR repeat 339..369 CDD:276809 6/29 (21%)
TPR_1 340..373 CDD:278916 7/32 (22%)
TPR repeat 374..402 CDD:276809 2/7 (29%)
JmjC 870..978 CDD:202224
CG31690NP_995615.2 DUF1736 272..340 CDD:285594
TPR_11 518..583 CDD:290150 20/76 (26%)
TPR repeat 518..546 CDD:276809 11/39 (28%)
TPR repeat 551..581 CDD:276809 7/29 (24%)
TPR_1 552..584 CDD:278916 8/31 (26%)
TPR 565..841 CDD:223533 53/291 (18%)
TPR repeat 586..611 CDD:276809 6/27 (22%)
TPR repeat 634..660 CDD:276809 5/25 (20%)
TPR repeat 671..699 CDD:276809 5/35 (14%)
TPR repeat 704..735 CDD:276809 3/30 (10%)
TPR repeat 740..768 CDD:276809 7/28 (25%)
TPR repeat 773..803 CDD:276809 10/33 (30%)
TPR 808..841 CDD:197478 7/32 (22%)
TPR repeat 808..836 CDD:276809 6/27 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.900

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