DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Utx and tomm34

DIOPT Version :9

Sequence 1:	NP_609368.3	Gene:	Utx / 34377	FlyBaseID:	FBgn0260749	Length:	1136	Species:	Drosophila melanogaster
Sequence 2:	NP_955932.2	Gene:	tomm34 / 323361	ZFINID:	ZDB-GENE-030131-2081	Length:	305	Species:	Danio rerio

Alignment Length:	147	Identity:	38/147 - (25%)
Similarity:	59/147 - (40%)	Gaps:	15/147 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 GQVHESKNSSDNKNAI--QKFEPSTQAGEHMENTSSRNNDDTKPFE-QDAKEKV--SIIEEKHQD 110
            ||.....:||...|.|  :|..|...|.:.........|...|..| :.|.||.  |:.::..:.
Zfish   160 GQAASPASSSQQNNVIDDKKKAPGPDAVKKGRTLKEEGNALVKKGEHKKAMEKYTQSLAQDPTEV 224

  Fly   111 EHYVN-ALCKLGHLHLLLGEYSEALSAYQKYLRFRENNYWTNHAFIYGIGVAYFKLRCFKWAIKS 174
            ..|.| |||     :|.|..|.:|:...::.||...    .|...:|....||.:|:..|..|:.
Zfish   225 TTYTNRALC-----YLALKMYKDAIRDCEEALRLDS----ANIKALYRRAQAYKELKNKKSCIED 280

  Fly   175 FQELLYLSPNFTCANEV 191
            ...:|.:.||.|...::
Zfish   281 LNSVLKIDPNNTAVQKL 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Utx	NP_609368.3	TPR repeat	147..181	CDD:276809	8/33 (24%)
		TPR_11	156..216	CDD:290150	10/36 (28%)
		TPR repeat	186..216	CDD:276809	1/6 (17%)
		TPR repeat	228..255	CDD:276809
		TPR_11	264..337	CDD:290150
		TPR repeat	265..300	CDD:276809
		TPR repeat	307..334	CDD:276809
		TPR_11	339..402	CDD:290150
		TPR repeat	339..369	CDD:276809
		TPR_1	340..373	CDD:278916
		TPR repeat	374..402	CDD:276809
		JmjC	870..978	CDD:202224
tomm34	NP_955932.2	TPR_11	13..83	CDD:290150
		TPR repeat	13..38	CDD:276809
		TPR repeat	43..81	CDD:276809
		TPR_11	54..116	CDD:290150
		TPR repeat	86..114	CDD:276809
		TPR_11	191..254	CDD:290150	18/67 (27%)
		TPR repeat	191..218	CDD:276809	7/26 (27%)
		TPR repeat	223..253	CDD:276809	10/34 (29%)
		TPR_11	226..289	CDD:290150	19/71 (27%)
		TPR	226..257	CDD:197478	11/39 (28%)
		TPR_1	258..291	CDD:278916	8/32 (25%)
		TPR repeat	258..286	CDD:276809	6/27 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900